1 Result for "

1642112-32-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1642112-32-0" in MCE Product Catalog:

Cat. No.: HY-108425A
CAS No.: 1642112-32-0
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

AMG8380, an orally active and less active enantiomer of AMG8379, can serves as a negative control. AMG8380 inhibits human and mouse voltage-gated sodium channel NaV1.7 with IC50s of 0.907 and 0.387 μM, respectively. AMG8380 blocks Tetrodotoxin (TTX)-sensitive native channels with an IC50 of 2560 nM .
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