2 Results for "

185197-71-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "185197-71-1" in MCE Product Catalog:

Cat. No.: HY-B0612B
CAS No.: 185197-71-1
Research Areas:  

Neurological Disease

(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism .
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Cat. No.: HY-B0612E
CAS No.: 184866-29-3
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent calcium channel blocker .
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