Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
19S regulatory particle
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "19S regulatory particle" in MCE Product Catalog:
Cat. No.: HY-159808
CAS No.: 875165-39-2
Target:
Research Areas:
TCL1 is a selective non-covalent inhibitor targeting the Pru domain of the Rpn-13 subunit in the 19S regulatory particle (19S RP) of the proteasome with an IC50 value of approximately 26 μM. TCL1 interferes with the recognition and transport of ubiquitinated proteins by Rpn-13, inhibits the degradation of proteins by the proteasome, and thus affects the balance of intracellular protein metabolism. TCL1 is promising for research of hematological malignancies .
Cat. No.: HY-P12182
Target:
Research Areas:
Mca-KKVAPYPME-Dap(Dnp)-NH2 is a fluorescent peptide substrate. Mca-KKVAPYPME-Dap(Dnp)-NH2 can be used to report ATP-dependent protease activities, such as those of the 26S Proteasome or ClpP protease .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
