2 Results for "

2,5-Epidithia-3,6-dioxopiperazine

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "2,5-Epidithia-3,6-dioxopiperazine" in MCE Product Catalog:

Cat. No.: HY-177477
CAS No.: 21056-79-1
2,5-Epidithia-3,6-dioxopiperazine (Formula 15) is a derivative of Epidithiodioxopiperazine (ETP). 2,5-Epidithia-3,6-dioxopiperazine improves intracellular penetration and restores the activity of 2-Cys-Prx (especially Peroxiredoxin II (PrxII)) of form simulation in cells. 2,5-Epidithia-3,6-dioxopiperazine inhibits PDGF-induced proliferation and migration in vascular smooth muscle cells while promoting these actions in endothelial cells with VEGF induction. 2,5-Epidithia-3,6-dioxopiperazine effectively inhibits the proliferation and migration and lung metastasis of melanoma cells. 2,5-Epidithia-3,6-dioxopiperazine can be used for vascular diseases such as hypertension, angina pectoris and myocardial infarction research .
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14
14 Cited Publications
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
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