1 Result for "

2413940-56-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2413940-56-2" in MCE Product Catalog:

Cat. No.: HY-147972
CAS No.: 2413940-56-2
Purity:  98.71%
Research Areas:  

Inflammation/Immunology

NF-κB/MAPK-IN-1 (compound 11a) is a potent inhibitor of NF-κB and MAPK pathway. NF-κB/MAPK-IN-1 shows inhibitory activity against NO production, with an IC50 of 6.96 µM. NF-κB/MAPK-IN-1 suppresses LPS-induced iNOS, COX-2, ERΚ and P38 signaling activation. NF-κB/MAPK-IN-1 can prevent LPS induced inflammatory response in macrophages. NF-κB/MAPK-IN-1 can be used for rheumatoid arthritis (RA) research .
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