1 Result for "

2734918-37-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2734918-37-5" in MCE Product Catalog:

Cat. No.: HY-143885
CAS No.: 2734918-37-5
Target:  

JAK

Research Areas:  

Inflammation/Immunology

JAK1/TYK2-IN-3 is a potent, selective and orally active dual TYK2/JAK1 inhibitor with IC50 values of 6 and 37 nM, respectively. JAK1/TYK2-IN-3 also shows selectively relative to JAK2 (IC50=140 nM) and JAK3 (IC50=362 nM). JAK1/TYK2-IN-3 shows anti-inflammatory effect by regulating the expression of related TYK2/JAK1-regulated genes, as well as the formation of Th1, Th2, and Th17 cells .
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