1 Result for "

2760536-88-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2760536-88-5" in MCE Product Catalog:

Cat. No.: HY-153953
CAS No.: 2760536-88-5
Target:  

Bcl-2 Family

Research Areas:  

Cancer

Bcl-2-IN-11 (compound 6) is a potent and selective Bcl-2 activity inhibitor, with an IC50 of 0.9 nM. Bcl-2-IN-11 shows weak inhibition of Bcl-xl (IC50 > 1000 nM). Bcl-2-IN-11 can be used for the research of a variety of cancers caused by abnormal overexpression of Bcl-2 family proteins: especially malignant hematologic diseases of acute lymphoid leukemia, etc. Bcl-2-IN-11 can also avoid toxic side effects caused by Bcl-xl inhibition, such as thrombocytopenia .
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