1 Result for "

2971782-66-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2971782-66-6" in MCE Product Catalog:

Cat. No.: HY-155758
CAS No.: 2971782-66-6
Research Areas:  

Cancer

hCA/VEGFR-2-IN-2 (compound 8g) is an indolinonylbenzenesulfonamide and a potential dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2. hCA/VEGFR-2-IN-2 inhibits VEGFR-2 (IC50=204 nM) and has high binding activity to hCAs, with Kis of 3.6 nM (hCA IX), 16.1 nM (hCA II), 16.7 nM (hCA XII), and 75.3 nM (hCA I), respectively. hCA/VEGFR-2-IN-2 has antiproliferative activity on VEGFR-2-overexpressing breast cancer cells .
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