1 Result for "

2988762-46-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2988762-46-3" in MCE Product Catalog:

Cat. No.: HY-159172
CAS No.: 2988762-46-3
Target:  

HDAC

Research Areas:  

Cancer

HDAC3-IN-4 is a selective and orally active HDAC3 inhibitor with an IC50 of 89 nM. HDAC3-IN-4 induces the degradation of PD-L1 by regulating cathepsin B (CTSB) in the lysosomes, with a DC50 of 5.7 μM. HDAC3-IN-4 shows better selectivity for HDAC3 over HDAC1, HDAC6, HDAC7, and HDAC8 .
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