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3'-NH2

" in MedChemExpress (MCE) Product Catalog:

2494

Inhibitors & Agonists

76

Fluorescent Dyes

211

Biochemical Assay Reagents

1721

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50

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Products

1

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18

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41

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39

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2

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0226
    TFLLR-NH2
    3 Publications Verification

    Protease Activated Receptor (PAR) Cardiovascular Disease
    TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.
    TFLLR-NH2
  • HY-P1260
    FSLLRY-NH2
    5+ Cited Publications

    Protease Activated Receptor (PAR) Neurological Disease
    FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor .
    FSLLRY-NH2
  • HY-175615

    ADC Payload Glutathione Peroxidase Ferroptosis Cancer
    RSL3-NH2 is a GPX4 inhibitor and ferroptosis inducer. RSL3-NH2 triggers the iron-dependent cell death pathway associated with lipid peroxidation by inhibiting GPX4 activity. RSL3-NH2 exhibits significant cytotoxicity against colorectal cancer cells and effectively induces their ferroptosis. RSL3-NH2 can serve as a ADC payload for synthesizing antibody-drug conjugates (ADC) and be used in colorectal cancer-related research .
    RSL3-NH2
  • HY-164569

    Radionuclide-Drug Conjugates (RDCs) Cancer
    NH2 DOTA-GA is a DOTA-based metal chelator that can be used to prepare radionuclide drug conjugates (RDCs) whose carboxylic acid groups can complex metal ions, for example, NH2 DOTA-GA complexes Gd(III) ions.
    NH2 DOTA-GA
  • HY-W017776

    SNAP-NH2

    Drug Intermediate Others
    BG-NH2 is a pharmaceutical intermediate. BG-NH2 is suitable for synthesizing fluorescent SNAP tag substrates to label RNA .
    BG-NH2
  • HY-W451406C

    PROTAC Linkers Others
    NH2-PEG2000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG2000-NH2
  • HY-P10201A

    STAT Cancer
    Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. Ac-GpYLPQTV-NH2 acetate has antitumor activity .
    Ac-GpYLPQTV-NH2 acetate
  • HY-P1263A
    tcY-NH2 TFA
    1 Publications Verification

    (trans-Cinnamoyl)-YPGKF-NH2 TFA

    Protease Activated Receptor (PAR) Metabolic Disease Inflammation/Immunology
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology [2] .
    tcY-NH2 TFA
  • HY-P1263
    tcY-NH2
    1 Publications Verification

    (trans-Cinnamoyl)-YPGKF-NH2

    Protease Activated Receptor (PAR) Metabolic Disease Inflammation/Immunology
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology [2] .
    tcY-NH2
  • HY-P10202

    STAT Cancer
    5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .
    5-FAM-GpYLPQTV-NH2
  • HY-P1310
    VKGILS-NH2
    1 Publications Verification

    Protease Activated Receptor (PAR) Inflammation/Immunology
    VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells [2].
    VKGILS-NH2
  • HY-P10201

    STAT Cancer
    Ac-GpYLPQTV-NH2 is a STAT3 inhibitor with an IC50 value of 0.33 μM. Ac-GpYLPQTV-NH2 has antitumor activity .
    Ac-GpYLPQTV-NH2
  • HY-P5360

    Protease Activated Receptor (PAR) Others
    TFLLRN-NH2 is a biological active peptide. (PAR-1 Agonist)
    TFLLRN-NH2
  • HY-130988

    GDC-0068-NH2; RG7440-NH2

    Ligands for Target Protein for PROTAC Cancer
    Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase .
    Ipatasertib-NH2
  • HY-131800

    ATP Synthase Metabolic Disease
    3'-NH2-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-NH2-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C [2].
    3'-NH2-ATP
  • HY-164181

    DNA/RNA Synthesis Phosphoramidites Cancer
    Fmoc-protected DMT-Dt PEG2 NH2 amidite is a phosphoramidite monomer.
    Fmoc-protected DMT-Dt PEG2 NH2 amidite
  • HY-W451406B

    Drug Intermediate Biochemical Assay Reagents Metabolic Disease
    NH2-PEG1000-NH2 is a double-ended amino polyethylene glycol with a number-average molecular weight of 1000, which serves as a synthetic raw material for adamantyl polyethylene glycol amine. NH2-PEG1000-NH2 can be used for the preparation of reduction-responsive liver-targeted polymeric micelles .
    NH2-PEG1000-NH2
  • HY-P6028

    N-myristoyltransferase Others
    GSNKSKPK-NH2 is a synthetic model peptide based on the c-Src N-terminal sequence and model peptide substrate for human NMT1 and NMT2.GSNKSKPK-NH2 facilitates in vitro assays measuring transfer of myristate or X10 fatty acid moieties .
    GSNKSKPK-NH2
  • HY-P3591

    Calcium Channel Neurological Disease
    YMRF-NH2 is a neuropeptide. YMRF-NH2 binds to FMRFa-R with an EC50 value of 31 nM [2].
    YMRF-NH2
  • HY-D2101

    Fluorescent Dye Others
    TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
    TAMRA-PEG3-NH2
  • HY-131800A

    Nucleoside Antimetabolite/Analog Others
    3'-NH2-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-NH2-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase .
    3'-NH2-ATP tetrasodium, 100 mM Solution
  • HY-D2602

    Fluorescent Dye Others
    ICG PEG5000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG5000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG5000 NH2
  • HY-D2599

    Fluorescent Dye Others
    ICG PEG1000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG1000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG1000 NH2
  • HY-P1311

    Drug Isomer Others
    RLLFT-NH2 is a reversed amino acid sequence negative control peptide for TFLLR-NH2 .
    RLLFT-NH2
  • HY-P11297

    Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    AC-SDKP-NH2 is a substrate peptide of Angiotensin converting enzyme (ACE). AC-SDKP-NH2 has anti-inflammatory and anti-fibrotic activities. AC-SDKP-NH2 directly acts on tissues and prevents or reverses them from excessive fibrosis, but fails to reduce blood pressure and left ventricular hypertrophy (LVH). AC-SDKP-NH2 attenuates inflammation and cell differentiation, proliferation and migration, therefore reducing fibrosis in the heart, vessels and kidneys in mice model. AC-SDKP-NH2 can be used for cardiovascular diseases such as hypertension research .
    AC-SDKP-NH2
  • HY-W128219

    CLIP-NH2

    Drug Intermediate Others
    BC-NH2 is a pharmaceutical intermediate. BC-NH2 can be used for synthesizing functional marker substrates .
    BC-NH2
  • HY-174902B

    OPSS-PEG1000-NH2

    Biochemical Assay Reagents Others
    PDP-PEG1000-NH2 (OPSS-PEG1000-NH2) is a PEG derivative that can be used for drug delivery research .
    PDP-PEG1000-NH2
  • HY-P11064

    Bacterial Infection
    G(IIKK)3I-NH2 is an antimicrobial peptide. G(IIKK)3I-NH2 exhibits potent antibacterial activity against both Gram-negative and Gram-positive bacteria. G(IIKK)3I-NH2 has low toxicity to primary cells and mice, and G(IIKK)3I-NH2 is not easy to induce bacterial resistance. G(IIKK)3I-NH2 can be used in the research of anti-infection agents .
    G(IIKK)3I-NH2
  • HY-168940E

    Biochemical Assay Reagents Cancer
    NH2-PEG600-COOH consists of an NH2 group, PEG units and a carboxyl group (-COOH). NH2-PEG600-COOH helps improve the biocompatibility of the resulting nanocomplexes in cancer cells. NH2-PEG600-COOH can be used in cancer-related research .
    NH2-PEG600-COOH
  • HY-103684

    Real Thiol-NH2

    Fluorescent Dye Neurological Disease
    RT-NH2 is a RealThiol prototype without the carboxylic acid groups. RT-NH2 is fairly hydrophobic and cannot distribute in the nucleus, which is a hallmark of protein binding for fluorescent probe.
    RT-NH2
  • HY-D2102

    Fluorescent Dye Others
    TAMRA-PEG7-NH2 is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.
    TAMRA-PEG7-NH2
  • HY-136008A

    VH032-PEG1-NH2 dihydrochloride

    E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs .
    (S,R,S)-AHPC-PEG1-NH2 dihydrochloride
  • HY-158704

    Biochemical Assay Reagents DNA/RNA Synthesis Others
    3'-NH2-ddTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
    3'-NH2-ddTTP sodium
  • HY-D2601

    Fluorescent Dye Others
    ICG PEG3400 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG3400 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG3400 NH2
  • HY-D2600

    Fluorescent Dye Others
    ICG PEG2000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG2000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG2000 NH2
  • HY-D2603

    Fluorescent Dye Others
    ICG PEG10000 NH2 is a polyethylene glycol derivative containing Indocyanine green (ICG) (HY-D0711) fluorescent dye and polyethylene glycol (PEG) and an amino group. The Indocyanine green fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. ICG PEG10000 NH2 can be used for fluorescence imaging, fluorescence tracing and fluorescence labeling (Ex/Em=785/813 nm).
    ICG PEG10000 NH2
  • HY-138523

    PROTAC Linkers Cancer
    NH2-PEG3500-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    NH2-PEG3500-NH2
  • HY-P10930

    DNA/RNA Synthesis Cancer
    wrwyar-NH2 (TFA) is a control peptide for wrwycr-NH2 (HY-P10930A) .
    wrwyar-NH2 TFA
  • HY-P1310A

    Protease Activated Receptor (PAR) Inflammation/Immunology
    VKGILS-NH2 TFA is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 TFA has no effect on DNA synthesis in cells [2].
    VKGILS-NH2 TFA
  • HY-W451406D

    PROTAC Linkers Others
    NH2-PEG10000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG10000-NH2
  • HY-W451406A

    PROTAC Linkers Others
    NH2-PEG5000-NH2 is a polyethylene glycol derivative containing two primary amine groups. The amino group can react quickly with activated carboxylic acid or carboxyl groups such as NHS esters to form stable amide bonds. The PEGylation of NH2-PEG-NH2 can increase solubility and stability, and reduce the immunogenicity of peptides and proteins, so it is mostly used to modify proteins, peptides and other substances.
    NH2-PEG5000-NH2
  • HY-P1311A

    Protease Activated Receptor (PAR) Others
    RLLFT-NH2 TFA is a reversed amino acid sequence negative control peptide for TFLLR-NH2 (HY-P0226) .
    RLLFT-NH2 TFA
  • HY-W339437

    PROTAC Linkers Cancer
    NH2-C3-PEG2-NH2 is a PROTAC linker that can be used in the synthesis of PROTACs.
    NH2-C3-PEG2-NH2
  • HY-P5638

    Bacterial Infection
    FLGFVGQALNALLGKL-NH2 is an antimicrobial peptide of frog origin. FLGFVGQALNALLGKL-NH2 has activity against Staphylococcus aureus ATCC 29213 (MIC=32 μM) .
    FLGFVGQALNALLGKL-NH2
  • HY-148872

    Biochemical Assay Reagents Others
    Thalidomide-5-NH2-C8-NH2 TFA can be used for compound synthesis .
    Thalidomide-5-NH2-C8-NH2 TFA
  • HY-P10667

    Integrin Cancer
    Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. Ac-MRGDH-NH2 can be used to synthesize the diastereoisomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic bis-aqua ruthenium warhead [Ru(Ph2phen)2(OH2)2]2+, and Ac-MRGDH-NH2 possesses integrin targeting ability and photosubstitution properties. Therefore, Ac-MRGDH-NH2 can be utilized in research on tumor-targeted photodynamic activation chemotherapy (PACT) .
    Ac-MRGDH-NH2
  • HY-P10673

    GHSR Metabolic Disease
    KwFwLL-NH2, a hexapeptide, is a ghrelin receptor ligand. KwFwLL-NH2 can act as a specific inverse agonist at the ghrelin receptor but with moderate potency (EC50=45.6 nM) .
    KwFwLL-NH2
  • HY-P10065

    Cathepsin Inflammation/Immunology
    RKLLW-NH2 is a Cathepsin L inhibitor .
    RKLLW-NH2
  • HY-P1312

    Protease Activated Receptor (PAR) Others
    LRGILS-NH2 is a reverse-sequence protease-activated receptor-2 (PAR-2)-inactive, negative control, and SLIGRL-NH2 is a PAR-2-activating peptide .
    LRGILS-NH2
  • HY-P10930A

    DNA/RNA Synthesis Cancer
    wrwycr-NH2 (TFA) is a peptide. wrwycr-NH2 (TFA) is cytotoxic to multiple cancer cells, can induce DNA damage and cell cycle arrest, but does not induce endoplasmic reticulum stress. wrwycr-NH2 (TFA) has anti-tumor activity, and it shows better efficacy when used in combination with DNA-damaging agents .
    wrwycr-NH2 TFA

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