1 Result for "

3039488-61-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3039488-61-1" in MCE Product Catalog:

Cat. No.: HY-178327
CAS No.: 3039488-61-1
Target:  

DGK Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

DGKα/ζ-IN-2 is a potent, orally active and selective dual DGKα/ζ inhibitor with IC50 values of 23 nM (DGKα) and 1.2 nM (DGKζ). DGKα/ζ-IN-2 exhibits selectivity over other DGK isoforms, such as DGKβ and DGKγ. DGKα/ζ-IN-2 shows robust and dose-dependent immune activation in the presence of antigen presentation in an OT-1 murine model. DGKα/ζ-IN-2 can be used for antitumor immunity .
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