1 Result for "

3052839-42-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3052839-42-3" in MCE Product Catalog:

Cat. No.: HY-155152
CAS No.: 3052839-42-3
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

P-gp/BCRP-IN-2 (compound 15) is an oxadiazole derivative and a dual inhibitor of the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). P-gp/BCRP-IN-2 also enhances the anti-proliferative effects of Doxorubicin (HY-15142A) in drug-resistant human adenocarcinoma colon cancer cell lines HT29/DX and MDCK-MDR1 cells .
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