1 Result for "

3075001-08-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3075001-08-7" in MCE Product Catalog:

Cat. No.: HY-161708
CAS No.: 3075001-08-7
Target:  

PROTACs CDK FLT3

Research Areas:  

Cancer

PROTAC FLT3/CDKs degrader-1 is a PROTAC degrader targeting CDKs and FLT3. PROTAC FLT3/CDKs degrader-1 degrades CDK2, CDK4, CDK6, CDK9 and FLT3 proteins via a ubiquitin-proteasome-dependent bivalent mechanism, with a DC50 of 18.73 nM against CDK2. PROTAC FLT3/CDKs degrader-1 promotes myeloid cell differentiation. PROTAC FLT3/CDKs degrader-1 inhibits leukemia cell proliferation. PROTAC FLT3/CDKs degrader-1 can be used for the research of acute myeloid leukemia .
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