1 Result for "

3098980-02-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3098980-02-7" in MCE Product Catalog:

Cat. No.: HY-162938
CAS No.: 3098980-02-7
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

Skp2 inhibitor 3 is an orally active inhibitor of the Skp2-Cks1 complex, with an IC50 of 4.86 μM. Skp2 inhibitor 3 reduces Skp2 protein expression while upregulating the expression of p21 and p27. Skp2 inhibitor 3 inhibits colony formation and migration of cancer cells, and induces cell cycle arrest at the S phase. Skp2 inhibitor 3 suppresses tumor growth in xenograft mice. Skp2 inhibitor 3 can be used in the research of gastric cancer and prostate cancer .
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