1 Result for "

3100306-42-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3100306-42-8" in MCE Product Catalog:

Cat. No.: HY-168274
CAS No.: 3100306-42-8
Research Areas:  

Cancer

PROTAC TRIB2 degrader-1 is a selective TRIB2 PROTAC degrader with a DC50 of 16.84 nM in PC3 cells. PROTAC TRIB2 degrader-1 directly interacts with TRIB2 and induces its degradation via the CRBN-dependent ubiquitin-proteasome pathway. PROTAC TRIB2 degrader-1 inhibits cancer cell proliferation and promotes apoptosis by inducing PARP cleavage. PROTAC TRIB2 degrader-1 is applicable to relevant research on prostate cancer .
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