2 Results for "

3cl peptide Inhibitors

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "3cl peptide Inhibitors" in MCE Product Catalog:

44
44 Cited Publications
Cat. No.: HY-10235
CAS No.: 402957-28-2
Purity:  99.54%
Synonyms: VX-950
Target:  

HCV Protease HCV SARS-CoV

Research Areas:  

Infection

Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide . Telaprevir inhibits SARS-CoV-2 3CL pro activity .
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Cat. No.: HY-152589
CAS No.: 2761367-25-1
Target:  

SARS-CoV

Research Areas:  

Infection

Antiviral agent 25 (compound 6g) is a new non-peptide analog covalent inhibitor of SARS-CoV-2 3CL pro. Antiviral agent 25 has a strong inhibitory effect on SARS-CoV-2 3CL pro and SARS-CoV-2 PL pro with IC50 values of 0.118 µM, 0.448 µM, respectively. Antiviral agent 25 has antiviral effect on SARS-CoV-2 with an EC50 value of 7.249 µM .
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