2761367-25-1
2761367-25-1
Chemical Structure
Antiviral agent 25
- CAS No.: 2761367-25-1
- Formula:C15H12FN3S
- Molecular Weight:285.34
IUPAC Name: (E)-3-(4-fluorophenyl)-N-methyl-2-phenyl-1,2,4-thiadiazol-5(2H)-imine
InChIKey: YBCTXELRRVXUMP-BMRADRMJSA-N
SMILES: C/N=C1N=C(N(S\1)C2=CC=CC=C2)C3=CC=C(C=C3)F
Biological Activity: Antiviral agent 25 (compound 6g) is a new non-peptide analog covalent inhibitor of SARS-CoV-2 3CLpro. Antiviral agent 25 has a strong inhibitory effect on SARS-CoV-2 3CLpro and SARS-CoV-2 PLpro with IC50 values of 0.118 µM, 0.448 µM, respectively. Antiviral agent 25 has antiviral effect on SARS-CoV-2 with an EC50 value of 7.249 µM[1].
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Antiviral agent 25 | Antiviral agent 25 (compound 6g) is a new non-peptide analog covalent inhibitor of SARS-CoV-2 3CLpro. Antiviral agent 25 has a strong inhibitory effect on SARS-CoV-2 3CLpro and SARS-CoV-2 PLpro with IC50 values of 0.118 µM, 0.448 µM, respectively. Antiviral agent 25 has antiviral effect on SARS-CoV-2 with an EC50 value of 7.249 µM. | |||||||||||||||||||||
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