Antiviral agent 25
Antiviral agent 25 (compound 6g) is a new non-peptide analog covalent inhibitor of SARS-CoV-2 3CLpro. Antiviral agent 25 has a strong inhibitory effect on SARS-CoV-2 3CLpro and SARS-CoV-2 PLpro with IC50 values of 0.118 µM, 0.448 µM, respectively. Antiviral agent 25 has antiviral effect on SARS-CoV-2 with an EC50 value of 7.249 µM.
For research use only. We do not sell to patients.
- CAS No.: 2761367-25-1
- Formula: C15H12FN3S
- Molecular Weight:285.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SARS-CoV-2 3CLpro 0.118 μM (IC50) |
SARS-CoV-2 PLpro 0.448 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | CC50 |
>100 μM
Compound: 6g
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Cytotoxicity against African green monkey Vero E6 cells incubated for 24 hrs by WST-8 assay
Cytotoxicity against African green monkey Vero E6 cells incubated for 24 hrs by WST-8 assay
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[PMID: 36702052] |
Chemical Information
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CAS No. 2761367-25-1
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Molecular Weight 285.34
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Formula C15H12FN3S
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SMILES
C/N=C1N=C(N(S\1)C2=CC=CC=C2)C3=CC=C(C=C3)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiviral agent 25 Related Classifications
HY-152589 Related Classifications
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