Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
5β-Cholestane
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "5β-Cholestane" in MCE Product Catalog:
Cat. No.: HY-W127488
CAS No.: 481-20-9
Synonyms: Coprostane
Cat. No.: HY-171949
CAS No.: 18866-87-0
Synonyms: 3α,7α,12α,25-Tetrahydroxycoprostane
Research Areas:
5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5) activator (EC50: 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX) .
Category:
Target:
Category:
Target:
Cat. No.: HY-E71945
Target:
Research Areas:
5β-Cholestane-3α,7α-diol 12α-hydroxylase (EC 1.14.13.96) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
Cat. No.: HY-E72010
Target:
Research Areas:
7α-Hydroxycholest-4-en-3-one 12α-hydroxylase (EC 1.14.18.8) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
Cat. No.: HY-P82418
Synonyms: CYP27A1; CYP27; Sterol 26-hydroxylase; mitochondrial; 5-beta-Cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; Cytochrome P-450C27/25; Cytochrome P450 27; Sterol 27-hydroxylase; Vitamin D(3) 25-hydroxylase
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
