1 Result for "

6-Tetrahydro-7H-pyrazolo[3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "6-Tetrahydro-7H-pyrazolo[3" in MCE Product Catalog:

Cat. No.: HY-179337
Research Areas:  

Neurological Disease

PDE2-IN-1 is a potent and orally active PDE2 inhibitor with an IC50 of 0.6 μM, demonstrating neuroprotective effects. PDE2-IN-1 modulates the PKA/CREB/BDNF signaling pathway by inhibiting PDE2. PDE2-IN-1 improves memory deficits and cognitive impairment in an okadai acid (OKA)-induced Alzheimer’s disease (AD) mouse model. PDE2-IN-1 can be used for the research of AD .
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