Search Result

Results for "

6-phosphate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Akt (1) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (5) Casein Kinase (1) Drug Derivative (4) Endogenous Metabolite (30) FBPase (3) Flavivirus (1) Glucose-6-Phosphate Isomerase (GPI) (3) Hexokinase (2) Isotope-Labeled Compounds (3) mTOR (5) PDI (1) PI3K (1) Reference Standards (4) TGF-beta/Smad (2) Virus Protease (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (4) Infection (3) Inflammation/Immunology (3) Metabolic Disease (29) Neurological Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-113407A

D-Fructose-6-phosphate disodium	Endogenous Metabolite FBPase	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate disodium is an endogenous metabolite. D-Fructose 6-phosphate disodium can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium can be used to study Lewy body dementia .

HY-112537

D-Glucose 6-phosphate 4 Publications Verification	Endogenous Metabolite mTOR	Cardiovascular Disease Metabolic Disease
D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure .

HY-W011184

6-Phosphogluconic acid trisodium	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Endogenous Metabolite Drug Derivative	Metabolic Disease
α,α-Trehalose 6-phosphate (Tre6P) potassium is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate potassium is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-128374

D-Glucose 6-phosphate disodium salt 4 Publications Verification	Endogenous Metabolite	Metabolic Disease
D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6 .

HY-N11848

D-Glucosamine 6-phosphate Glucosamine-6-phosphate; D-GlcN-6-P	Endogenous Metabolite	Metabolic Disease
D-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). D-Glucosamine 6-phosphate can be used for the research of diabetes mellitus .

HY-112537B

D-Glucose 6-phosphate sodium 3 Publications Verification	Endogenous Metabolite	Metabolic Disease
D-Glucose 6-phosphate sodium is an endogenous metabolite.

HY-113514

6-Phosphogluconic acid	Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-139409A

2-Deoxy-D-glucose 6-phosphate disodium 2 Publications Verification	Hexokinase Glucose-6-Phosphate Isomerase (GPI)	Cancer
2-Deoxy-D-glucose 6-phosphate disodium is an ATP-competitive, 2-deoxy-D-glucose non-competitive Hexokinase inhibitor, with a K_i value of 1.45 mM against bovine heart hexokinase. 2-Deoxy-D-glucose 6-phosphate disodium exerts ATP-competitive and 2-deoxy-D-glucose non-competitive inhibitory effects on bovine heart hexokinase. 2-DG inhibits glycolysis via the production and intracellular accumulation of 2-Deoxy-D-glucose 6-phosphate disodium, thereby inhibiting the functions of hexokinase and Glucose-6-phosphate isomerase, and inducing cell death. 2-Deoxy-D-glucose 6-phosphate disodium can be used in cancer-related research .

HY-112537S1

D-Glucose 6-Phosphate-13C6 (disodium xhydrate)	Isotope-Labeled Compounds Endogenous Metabolite mTOR	Cardiovascular Disease Metabolic Disease
D-Glucose 6-Phosphate- ¹³C₆ disodium xhydrate is a ¹³C-labeled D-Glucose 6-phosphate disodium xhydrate. D-Glucose 6-phosphate disodium xhydrate is a key central node metabolite in sugar metabolism, serving as the initial metabolite of glycolysis and pentose phosphate pathway, and also a substrate for glycogen synthesis. D-Glucose 6-phosphate disodium xhydrate can act as a metabolic stress signal, especially when phosphoglucomutase (PGI) is inhibited, activating the mTOR pathway, promoting protein synthesis, and thereby participating in the remodeling process of the heart. D-Glucose 6-phosphate disodium xhydrate can be used in research related to non-insulin-dependent diabetes and heart failure.

HY-113407

D-Fructose-6-phosphate	Endogenous Metabolite FBPase	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia .

HY-112253

D-Fructose 1-phosphate	Endogenous Metabolite	Metabolic Disease
D-Fructose 1-phosphate is a key intermediate metabolite in the fructose metabolic pathway. As a key signaling molecule linking fructose metabolism and glucose metabolic regulation, D-Fructose 1-phosphate acts as an allosteric modulator to counteract the inhibitory effect of the glucokinase-regulatory protein complex, thereby finely regulating the direction of hepatic glucose metabolism at the substrate level .

HY-160821A

N-Acetylmannosamine 6-phosphate sodium salt ManNAc-6P sodium salt	Endogenous Metabolite	Others
N-Acetylmannosamine 6-phosphate sodium salt is a NanR modulator and an intermediate in the sialic acid pathway. N-Acetylmannosamine 6-phosphate sodium salt disrupts the binding of NanR to the promoter regions of nanAT and nanE, and prevents NanR-mediated transcriptional repression of these loci. N-Acetylmannosamine 6-phosphate sodium salt acts as a key precursor for sialic acid biosynthesis, participating in this process via Neu5Ac-9-P synthase. N-Acetylmannosamine 6-phosphate sodium salt can be used in research related to GNE myopathy .

HY-N6841

Rhodiolin 1 Publications Verification	Glucose-6-Phosphate Isomerase (GPI) Casein Kinase Virus Protease Flavivirus PI3K Akt mTOR Apoptosis	Infection Cancer
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing PI3K/AKT/mTOR phosphorylation and induce apoptosis. Rhodiolin as a NS2B-NS3 protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral .

HY-W718136

D-Glucosamine 6-phosphate sodium GlcN6P-Na	Biochemical Assay Reagents	Others
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-167805

D-Glucose 6-phosphate potassium	Biochemical Assay Reagents
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-128374R

D-Glucose 6-phosphate disodium salt (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
D-Glucose 6-phosphate disodium salt (Standard) is the analytical standard of D-Glucose 6-phosphate disodium salt (HY-128374). This product is intended for research and analytical applications. D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6.

HY-N11848R

D-Glucosamine 6-phosphate (Standard) Glucosamine-6-phosphate (Standard)	Endogenous Metabolite Reference Standards	Metabolic Disease
D-Glucosamine 6-phosphate (Glucosamine-6-phosphate; D-GlcN-6-P) (Standard) is an analytical standard for D-Glucosamine 6-phosphate. This product is used for research and analytical applications. D-Glucosamine 6-phosphate is a phosphorylated amino sugar synthesized by glutamine fructose-6-phosphate aminotransferase (GFAT). The expression level of D-Glucosamine 6-phosphate is regulated by glucose and glutamine concentrations .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Endogenous Metabolite Drug Derivative	Metabolic Disease
α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-112537S2

D-Glucose 6-phosphate-13C	Isotope-Labeled Compounds Endogenous Metabolite mTOR	Others
D-Glucose 6-phosphate- ¹³C is ¹³C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure.

HY-W612338

9-Oxononanoic acid 9-ONA	Acetyl-CoA Carboxylase	Inflammation/Immunology
9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis .

HY-P2918

Phosphoglucose Isomerase, Rabbit muscle GPI; Phosphoglucose Isomerase	Endogenous Metabolite	Metabolic Disease Cancer
Phosphoglucose Isomerase, Rabbit muscle (GPI), i.e., phosphoglucose isomerase/phosphoglucoisomerase (PGI) or phosphohexose isomerase (PHI), is often used in biochemical studies. Glucose 6-phosphate isomeras is a highly conserved glycolytic and dimeric enzyme. Glucose 6-phosphate isomeras catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate .

HY-125863B

Glucose 6-phosphate dehydrogenase (yeast, recombinant) G6PD (yeast, recombinant)	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Cancer
Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. Glucose 6-phosphate dehydrogenase helps cells resist oxidative stress and regulates metabolic rates. It holds potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy .

HY-147062

N-Acetyl-D-galactosamine-6-phosphate	Biochemical Assay Reagents	Metabolic Disease
N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). N-Acetyl-D-galactosamine-6-phosphate can be hydrolyze by NagA .

HY-139409

2-Deoxy-D-glucose 6-phosphate	Hexokinase Glucose-6-Phosphate Isomerase (GPI)	Cancer
2-Deoxy-D-glucose 6-phosphate disodium is an ATP-competitive and 2-deoxy-D-glucose non-competitive Hexokinase inhibitor, with a K_i value of 1.45 mM against bovine heart hexokinase. 2-Deoxy-D-glucose 6-phosphate disodium exerts ATP-competitive and 2-deoxy-D-glucose non-competitive inhibitory effects on bovine heart hexokinase. 2-DG inhibits glycolysis via the generation and intracellular accumulation of 2-Deoxy-D-glucose 6-phosphate disodium, thereby inhibiting the functions of hexokinase and Glucose-6-phosphate isomerase, and inducing cell death. 2-Deoxy-D-glucose 6-phosphate disodium can be used in cancer-related research .

HY-W011184R

6-Phosphogluconic acid trisodium (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.

HY-112537A

D-Glucose 6-phosphate dipotassium	Endogenous Metabolite mTOR	Cardiovascular Disease Metabolic Disease
D-Glucose 6-phosphate dipotassium is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate dipotassium acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate dipotassium can be used in research related to non-insulin-dependent diabetes mellitus and heart failure .

HY-N15740

Chondrosamine, 6-phosphate	Endogenous Metabolite	Others
Chondrosamine, 6-phosphate is an amino sugar phosphate compound that participates in sugar metabolism and amino sugar metabolic pathways .

HY-W725496

D-Fructose 6-phosphate dipotassium	Endogenous Metabolite	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

HY-W654206

D-Glucose 6-Phosphate Sodium Salt Hydrate-13C6	Isotope-Labeled Compounds	Others
D-Glucose 6-Phosphate Sodium Salt Hydrate- ¹³C₆ is the ¹³C-labeled D-Glucose 6-Phosphate Sodium Salt Hydrate.

HY-131368R

α,α-Trehalose 6-phosphate potassium (Standard) Tre6P potassium (Standard)	Endogenous Metabolite Drug Derivative Reference Standards	Others
α,α-Trehalose 6-phosphate potassium (Standard) is the analytical standard of α,α-Trehalose 6-phosphate potassium (HY-131368). This product is intended for research and analytical applications. α,α-Trehalose 6-phosphate (Tre6P) potassium is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate potassium is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-E70407

Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli 1-5-Anhydroglucitol-6-phosphate dehydrogenase, escherichia coli	Endogenous Metabolite	Metabolic Disease
Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli is a dehydrogenase produced by E. coli. Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli can catalyze the conversion between D-sorbitol 6-phosphate and D-fructose 6-phosphate, with the oxidation of D-sorbitol 6-phosphate happening at a rate 10 times faster than the reduction of D-fructose 6-phosphate, and it plays a role in various cellular processes .

HY-139409B

2-Deoxy-D-glucose 6-phosphate sodium	Drug Derivative	Metabolic Disease
2-Deoxy-D-glucose 6-phosphate sodium, a derivative of 2-Deoxy-D-glucose (HY-13966), is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .

HY-W145606

D-Glucose-6-Phosphate barium salt heptahydrate	Biochemical Assay Reagents	Others
D-Glucose 6-Phosphate Barium Salt Heptahydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2918D

Phosphoglucose isomerase, E.coli	Endogenous Metabolite	Metabolic Disease
Phosphoglucose isomerase, E.coli (EC 5.3.1.9) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. Phosphoglucose isomerase is responsible for the second step of glycolysis and is involved in glucogenesis.

HY-P2918E

Phosphoglucose isomerase, Bacillus subtilis	Endogenous Metabolite	Metabolic Disease
Phosphoglucose isomerase, Bacillus subtilis (EC 5.3.1.9) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. Phosphoglucose isomerase is responsible for the second step of glycolysis and is involved in glucogenesis.

HY-P2918C

Phosphoglucose isomerase, Saccharomyces cerevisiae	Endogenous Metabolite	Metabolic Disease
Phosphoglucose isomerase, Saccharomyces cerevisiae (EC 5.3.1.9) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. Phosphoglucose isomerase is responsible for the second step of glycolysis and is involved in glucogenesis.

HY-113407B

D-Fructose-6-phosphate disodium hydrate	Endogenous Metabolite FBPase	Neurological Disease Metabolic Disease
D-Fructose 6-phosphate disodium hydrate is an endogenous metabolite. D-Fructose 6-phosphate disodium hydrate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium hydrate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium hydrate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium hydrate can be used to study Lewy body dementia .

HY-181430

PXS 25	TGF-beta/Smad	Metabolic Disease Inflammation/Immunology
PXS 25 is a cation-independent mannose 6-phosphate receptor (CI-M6PR) inhibitor that inhibits *CI-M6PR*-mediated activation of latent TGF-β₁. PXS 25 inhibits conversion of high glucose-induced latent TGF-β₁ to active TGF-β₁ in proximal tubule cells under normoxic conditions. PXS 25 suppresses high glucose-induced fibronectin, collagen IV production, and phosphorylated Smad 2 in proximal tubule cells under normoxic conditions. PXS 25 has antifibrotic properties in skin fibroblasts. PXS 25 can be used for the research of diabetic nephropathy .

HY-E71021

Transaldolase, Baker's yeast (S. cerevisiae)	Endogenous Metabolite	Metabolic Disease
Transaldolase, Baker's yeast (S. cerevisiae) (EC 2.2.1.2) is an enzyme of the non-oxidative phase of the pentose phosphate pathway. The following chemical reaction is catalyzed by transaldolase:sedoheptulose 7-phosphate + glyceraldehyde 3-phosphate? erythrose 4-phosphate + fructose 6-phosphate.

HY-P2820C

Phosphoglucomutase, Chicken	Biochemical Assay Reagents	Metabolic Disease
Phosphoglucomutase, Chicken (EC 5.4.2.2) is an enzyme that transfers a phosphate group on an α-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction. Phosphoglucomutase, Chicken (EC 5.4.2.2) facilitates the interconversion of glucose 1-phosphate and glucose 6-phosphate.

HY-W248922

2,6-Dibromo-4-(hydroxymethyl)phenol	PDI	Infection
2,6-Dibromo-4-(hydroxymethyl) phenol (Compound 5) acts as a selective inhibitor of Saccharomyces cerevisiae glucose-6-phosphate dehydrogenase, with an IC50 value of 50.2 μM, and shows no activity against Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase .

HY-181431

PXS 64	TGF-beta/Smad	Inflammation/Immunology
PXS 64, a mannose-6-phosphate (M6P) analogue. a lipophilic prodrug of PXS 25 (HY-181430). PXS 64 is an effective anti-fibrotic agent by inhibiting the activation of latent TGF-β1. PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts. PXS 64 reduces TGFβ-mediated collagen IV, fibronectin, MCP-1, and phospho-smad2 expression in kidney cells. PXS 64 reduces collagen deposition in dermal scar fibroblasts. PXS 64 can be used for the research of chronic kidney disease, idiopathic pulmonary fibrosis, scarring .

HY-N18991

D-Mannitol 1-phosphate	Endogenous Metabolite Bacterial	Infection
D-Mannitol 1-phosphate is a non-nucleotide phosphate ester. D-Mannitol 1-phosphate is isolable from Lactobacillus arabinosus. D-Mannitol 1-phosphate is associated with active polyol metabolism in Lactobacillus arabinosus .

Cat. No.	Product Name	Type

HY-W718136

D-Glucosamine 6-phosphate sodium GlcN6P-Na	Biochemical Assay Reagents
D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

D-Glucosamine 6-phosphate sodium

GlcN6P-Na

Biochemical Assay Reagents

D-Glucosamine 6-phosphate (sodium) (GlcN6P-Na) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-167805

D-Glucose 6-phosphate potassium	Biochemical Assay Reagents
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-112537A

D-Glucose 6-phosphate dipotassium

Biochemical Assay Reagents

D-Glucose 6-phosphate dipotassium is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate dipotassium acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate dipotassium can be used in research related to non-insulin-dependent diabetes mellitus and heart failure .

HY-W725496

D-Fructose 6-phosphate dipotassium

Biochemical Assay Reagents

D-Fructose 6-phosphate dipotassium is an endogenous metabolite in saliva that affects cell growth and autophagy; it can be hydrolyzed by Fructose-1,6-bisphosphatase (FBPase). D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537) by the action of phosphoglucose isomerase. D-Fructose 6-phosphate dipotassium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose 6-phosphate dipotassium can be used to study Lewy body dementia .

HY-W145606

D-Glucose-6-Phosphate barium salt heptahydrate	Biochemical Assay Reagents
D-Glucose 6-Phosphate Barium Salt Heptahydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113407A

D-Fructose-6-phosphate disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite FBPase
D-Fructose 6-phosphate disodium is an endogenous metabolite. D-Fructose 6-phosphate disodium can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium can be used to study Lewy body dementia .

HY-112537

D-Glucose 6-phosphate 4 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite mTOR
D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure .

HY-W011184

6-Phosphogluconic acid trisodium	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Structural Classification Arabidopsis thaliana (L.) Heynh. Plants Brassicaceae Saccharides Source Classification	Endogenous Metabolite Drug Derivative
α,α-Trehalose 6-phosphate (Tre6P) potassium is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate potassium is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-128374

D-Glucose 6-phosphate disodium salt 4 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6 .

HY-N11848

D-Glucosamine 6-phosphate Glucosamine-6-phosphate; D-GlcN-6-P	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Monosaccharides Source Classification	Endogenous Metabolite
D-Glucosamine 6-phosphate is an endogenous metabolite that can be synthesized by glutamine fructose-6-phosphate amidotransferase (GFAT). D-Glucosamine 6-phosphate can be used for the research of diabetes mellitus .

HY-112537B

D-Glucose 6-phosphate sodium 3 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Glucose 6-phosphate sodium is an endogenous metabolite.

HY-113514

6-Phosphogluconic acid	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
6-Phosphogluconic acid is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid is an endogenous metabolite .

HY-113407

D-Fructose-6-phosphate	Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite FBPase
D-Fructose 6-phosphate is an endogenous metabolite. D-Fructose 6-phosphate can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate can be used to study Lewy body dementia .

HY-112253

D-Fructose 1-phosphate	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite
D-Fructose 1-phosphate is a key intermediate metabolite in the fructose metabolic pathway. As a key signaling molecule linking fructose metabolism and glucose metabolic regulation, D-Fructose 1-phosphate acts as an allosteric modulator to counteract the inhibitory effect of the glucokinase-regulatory protein complex, thereby finely regulating the direction of hepatic glucose metabolism at the substrate level .

HY-N6841

Rhodiolin 1 Publications Verification	Flavonols Flavonoids Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Glucose-6-Phosphate Isomerase (GPI) Casein Kinase Virus Protease Flavivirus PI3K Akt mTOR Apoptosis
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing PI3K/AKT/mTOR phosphorylation and induce apoptosis. Rhodiolin as a NS2B-NS3 protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral .

HY-N11848R

D-Glucosamine 6-phosphate (Standard) Glucosamine-6-phosphate (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Saccharides Monosaccharides Source Classification	Endogenous Metabolite Reference Standards
D-Glucosamine 6-phosphate (Glucosamine-6-phosphate; D-GlcN-6-P) (Standard) is an analytical standard for D-Glucosamine 6-phosphate. This product is used for research and analytical applications. D-Glucosamine 6-phosphate is a phosphorylated amino sugar synthesized by glutamine fructose-6-phosphate aminotransferase (GFAT). The expression level of D-Glucosamine 6-phosphate is regulated by glucose and glutamine concentrations .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Endogenous metabolite Saccharides Source Classification	Endogenous Metabolite Drug Derivative
α,α-Trehalose 6-phosphate (Tre6P) is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-W612338

9-Oxononanoic acid 9-ONA	Structural Classification Arachis hypogaea L. Leguminosae Ketones, Aldehydes, Acids Plants Source Classification	Acetyl-CoA Carboxylase
9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis .

HY-W011184R

6-Phosphogluconic acid trisodium (Standard)	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with K_is of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.

HY-N15740

Chondrosamine, 6-phosphate	Natural Products Endogenous metabolite Source Classification	Endogenous Metabolite
Chondrosamine, 6-phosphate is an amino sugar phosphate compound that participates in sugar metabolism and amino sugar metabolic pathways .

HY-131368R

α,α-Trehalose 6-phosphate potassium (Standard) Tre6P potassium (Standard)	Structural Classification Arabidopsis thaliana (L.) Heynh. Plants Brassicaceae Saccharides Source Classification	Endogenous Metabolite Drug Derivative Reference Standards
α,α-Trehalose 6-phosphate potassium (Standard) is the analytical standard of α,α-Trehalose 6-phosphate potassium (HY-131368). This product is intended for research and analytical applications. α,α-Trehalose 6-phosphate (Tre6P) potassium is a glucose analogue with potent anti-hyperglcaemic activity. α,α-Trehalose 6-phosphate potassium is rapidly converted to the end product, α,α′-trehalose, through the action of α,α-Trehalose 6-phosphate phosphatase (T6PP) .

HY-N18991

D-Mannitol 1-phosphate	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Endogenous Metabolite Bacterial
D-Mannitol 1-phosphate is a non-nucleotide phosphate ester. D-Mannitol 1-phosphate is isolable from Lactobacillus arabinosus. D-Mannitol 1-phosphate is associated with active polyol metabolism in Lactobacillus arabinosus .

Cat. No.	Product Name	Chemical Structure

HY-112537S1

D-Glucose 6-Phosphate-13C6 (disodium xhydrate)

D-Glucose 6-Phosphate- ¹³C₆ disodium xhydrate is a ¹³C-labeled D-Glucose 6-phosphate disodium xhydrate. D-Glucose 6-phosphate disodium xhydrate is a key central node metabolite in sugar metabolism, serving as the initial metabolite of glycolysis and pentose phosphate pathway, and also a substrate for glycogen synthesis. D-Glucose 6-phosphate disodium xhydrate can act as a metabolic stress signal, especially when phosphoglucomutase (PGI) is inhibited, activating the mTOR pathway, promoting protein synthesis, and thereby participating in the remodeling process of the heart. D-Glucose 6-phosphate disodium xhydrate can be used in research related to non-insulin-dependent diabetes and heart failure.

HY-112537S2

D-Glucose 6-phosphate-13C

D-Glucose 6-phosphate- ¹³C is ¹³C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is a key central node metabolite in glucose metabolism. It serves as the initiating metabolite for glycolysis and the pentose phosphate pathway, as well as a substrate for glycogen synthesis. D-Glucose 6-phosphate acts as a metabolic stress signal, which activates the mTOR pathway to promote protein synthesis, especially when phosphoglucose isomerase (PGI) is inhibited, thereby participating in cardiac remodeling processes. D-Glucose 6-phosphate can be used in research related to non-insulin-dependent diabetes mellitus and heart failure.

HY-W654206

D-Glucose 6-Phosphate Sodium Salt Hydrate-13C6
D-Glucose 6-Phosphate Sodium Salt Hydrate- ¹³C₆ is the ¹³C-labeled D-Glucose 6-Phosphate Sodium Salt Hydrate.

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81754

	IGF2R Antibody (YA1499) IGF2R; MPRI; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	IGF2R Antibody (YA1499) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IGF2R.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

6-phosphate

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Natural
Products