1 Result for "

8-Bromo-AMP

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "8-Bromo-AMP" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-134266
CAS No.: 23567-96-6
Purity:  98.81%
Synonyms: 8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid
8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is an AMP analog. 8-Bromo-AMP inhibits ADP-dependent glucokinase (ADPGK). 8-Bromo-AMP competitively inhibits ADPGK by binding to the nucleotide-binding site, inducing conformational changes, and acting on catalytic residues. 8-Bromo-AMP non-competitively inhibits rat adenylate kinase isozymes AK-M, AK II, and AK III. 8-Bromo-AMP inhibits T cell activation-induced ROS production and ROS-dependent IL-2 and IκB expression. 8-Bromo-AMP is used in research on cancer and myocardial ischemia-reperfusion injury [8] .
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