1 Result for "

851378-93-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "851378-93-3" in MCE Product Catalog:

Cat. No.: HY-130309
CAS No.: 851378-93-3
Synonyms: (±)8,9-EEQ; (±)8,9-epoxy Eicosatetraenoic acid
Eicosapentaenoic acid (EPA) is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE, relaxes vascular and airway smooth muscle by activating large conductance Ca 2+-activated K + (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo.
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