2 Results for "

9,10-Phenanthrenequinone

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "9,10-Phenanthrenequinone" in MCE Product Catalog:

Cat. No.: HY-W014507
CAS No.: 84-11-7
Target:  

Claudin

Research Areas:  

Cancer

9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis .
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Cat. No.: HY-W016470
CAS No.: 776-35-2
9,10-Dihydrophenanthrene is an analogue of 9,10-Phenanthrenequinone (HY-W014507). 9,10-Dihydrophenanthrene loses its anti-tumor activity that induces apoptosis in HCT-116 and HL-60 tumor cells .
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