84-11-7
84-11-7
Chemical Structure
9,10-Phenanthrenequinone
- CAS No.: 84-11-7
- Formula:C14H8O2
- Molecular Weight:208.21
IUPAC Name: phenanthrene-9,10-dione
InChIKey: YYVYAPXYZVYDHN-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC=C2C3=CC=CC=C3C1=O
Biological Activity: 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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9,10-Phenanthrenequinone | 99.72% | 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis. | ||||||||||||||||||||
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