84-11-7

9,10-Phenanthrenequinone Chemical Structure
84-11-7

Chemical Structure

9,10-Phenanthrenequinone

  • CAS No.: 84-11-7
  • Formula:C14H8O2
  • Molecular Weight:208.21

IUPAC Name: phenanthrene-9,10-dione

InChIKey: YYVYAPXYZVYDHN-UHFFFAOYSA-N

SMILES: O=C1C2=CC=CC=C2C3=CC=CC=C3C1=O

Biological Activity: 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis[1].

Cat. No. Product Name Purity Description Pricing
HY-W014507 		9,10-Phenanthrenequinone 99.72% 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis.
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