84-11-7
84-11-7
Chemical Structure
9,10-Phenanthrenequinone
- CAS No.: 84-11-7
- Formula:C14H8O2
- Molecular Weight:208.21
IUPAC Name: phenanthrene-9,10-dione
InChIKey: YYVYAPXYZVYDHN-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC=C2C3=CC=CC=C3C1=O
Biological Activity: 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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9,10-Phenanthrenequinone | 99.72% | 9,10-Phenanthrenequinone is an inhibitor of claudin-5/CLDN5 that induces apoptosis via a NO synthase/ROS-dependent mechanism. 9,10-Phenanthrenequinone also promotes endothelial barrier dysfunction by promoting caspase activation and DNA fragmentation, and reducing CLDN5 expression and proteasomal proteolysis. | ||||||||||||||||||||
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DSP-0565 | DSP-0565 (compound 17a) is a strong, broad-spectrum anti-epileptic agent (AED) candidate with unique GABAergic function. DSP-0565 shows anti-convulsant activity in various models (scPTZ, MES, 6 Hz and amygdala kindling) with good safety margin. | |||||||||||||||||||||
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2-Nitrophenanthraquinone | 2-Nitrophenanthraquinone is a bluish-black substance that can be used to dye fine wool, either chrome-mordanted or unmordanted. | |||||||||||||||||||||
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SF1670 | 98.57% | SF1670 is a potent and specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor. | ||||||||||||||||||||
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1-(9H-Fluoren-9-yl)ethanol | 1-(9H-Fluoren-9-yl)ethanol is a prominent fragment in β-lactam antibiotic modification and an important building block for anti-inflammatory agent. | |||||||||||||||||||||
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Dibenzosuberone | 99.84% | Dibenzosuberone is a tricyclic compound, commonly referred to as a tricyclic antidepressant (TCA), and is widely used in research on migraine, tension-type headache, anxiety disorder and schizophrenia. Dibenzosuberone also serves as a key intermediate for the synthesis of various active pharmaceutical ingredients (APIs) (e.g., amitriptyline (HY-B0527), nortriptyline (HY-118620), nortriptyline or cyproheptadine (HY-B1622)). | ||||||||||||||||||||
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Benzil (Standard) | ≥98% | Benzil (Standard) is the analytical standard of Benzil. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Phenindione | 98.21% | Phenindione is an anticoagulant and can act as a vitamin K antagonist. | ||||||||||||||||||||
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5H-Dibenzo[b,f]azepin-10(11H)-one (Standard) | ≥98% | 5H-Dibenzo[b,f]azepin-10(11H)-one (Standard) is the analytical standard of 5H-Dibenzo[b,f]azepin-10(11H)-one. This product is intended for research and analytical applications. | ||||||||||||||||||||
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5,6-Chrysenedione | 99.87% | 5,6-Chrysenedione is the photochemical degradation product of 6-Aminochrysene (HY-108315). | ||||||||||||||||||||
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Diphenic acid | Diphenic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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