4 Results for "

Aβ42 fibrillation

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Aβ42 fibrillation" in MCE Product Catalog:

Cat. No.: HY-W440556
CAS No.: 137407-62-6
Synonyms: 4-Sulfocalix[8]arene
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

GL-522 (4-Sulfocalix[8]arene) is a Aβ42 inhibitor. GL-522 bind to Aβ42 through nonspecific and multipoint hydrophobic interactions with a Kd of 276  μM. GL-522 effectively inhibits Aβ42 fibrillation and reduces amyloid cytotoxicity. GL-522 can be used for Alzheimer's disease research .
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Cat. No.: HY-W440555
CAS No.: 112269-92-8
Synonyms: para-Sulfonatocalix[n]arene
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

4-Sulfocalix[4]arene (para-Sulfonatocalix[n]arene) is a amyloid-beta 42 binder with a Kd of 5.39 M. 4-Sulfocalix[4]arene can inhibit amyloid β-peptide fibrillation and reduce amyloid cytotoxicity .
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Cat. No.: HY-N17929
CAS No.: 93078-67-2
Doliroside A is an Aβ42-binding agent with an IC50 of 26.57 μM for Aβ42. Doliroside A binds to Aβ42 nuclei and oligomers to form stable complexes, suppresses Aβ42 fibrillation, and redirects Aβ42 into off-pathway, amorphous oligomers. Doliroside A can be used for the research of alzheimer’s disease (ad) .
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Cat. No.: HY-175755
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Ac-BIM-acid bromide is a derivative of Acridine. Ac-BIM-acid bromide significantly inhibits amyloid fibrillation. Ac-BIM-acid bromide modulates the structure of N-terminal region of Saccharomyces cerevisiae Stm1 protein (Stm1_N 1-113) and the amyloid morphology of human Aβ42 protein, inhibiting theirs growth. Ac-BIM-acid bromide can be used for Alzheimer’s disease research .
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