GL-522
GL-522 (4-Sulfocalix[8]arene) is a Aβ42 inhibitor. GL-522 bind to Aβ42 through nonspecific and multipoint hydrophobic interactions with a Kd of 276 μM. GL-522 effectively inhibits Aβ42 fibrillation and reduces amyloid cytotoxicity. GL-522 can be used for Alzheimer's disease research.
For research use only. We do not sell to patients.
- CAS No.: 137407-62-6
- Formula: C56H48O32S8
- Molecular Weight:1489.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 137407-62-6
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Molecular Weight 1489.48
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Formula C56H48O32S8
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SMILES
O=S(O)(C1=CC(CC2=CC(S(=O)(O)=O)=CC(CC3=CC(S(=O)(O)=O)=CC(CC4=CC(S(=O)(O)=O)=CC(CC5=C(O)C(CC6=C(O)C(CC7=C(O)C(CC8=C(O)C(C9)=CC(S(=O)(O)=O)=C8)=CC(S(=O)(O)=O)=C7)=CC(S(=O)(O)=O)=C6)=CC(S(=O)(O)=O)=C5)=C4O)=C3O)=C2O)=C(O)C9=C1)=O
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Synonyms
4-Sulfocalix[8]arene
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)