Search Result
Results for "
ABTS
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-15902
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AzBTS-(NH4)2
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Fluorescent Dye
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Others
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ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .
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- HY-N0828
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Autophagy
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Inflammation/Immunology
Cancer
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Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .
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- HY-N0778
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Xanthine Oxidase
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Endocrinology
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Isorhamnetin-3-O-neohespeidoside is a flavonoid. Isorhamnetin-3-O-neohespeidoside can be isolated from Typha angustifolia. Isorhamnetin-3-O-neohespeidoside inhibits xanthine oxidase activity with an IC50 of 48.75 μg mL. Isorhamnetin-3-O-neohespeidoside has antioxidant and osteoclastogenic activities. Isorhamnetin-3-O-neohespeidoside can be used in research of bone .
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- HY-W047187
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Xanthine Oxidase
NO Synthase
TNF Receptor
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Others
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Lavandoside is an ABTS ?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC50 of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .
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- HY-N7005
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- HY-N0627
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LDLR
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Others
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Kaempferol-7-O-β-D-glucopyranoside is a flavonoid glycoside. Kaempferol-7-O-β-D-glucopyranoside exists in the root bark of Cudrania tricuspidata. Kaempferol-7-O-β-D-glucopyranoside inhibits Cu 2+-induced lipid peroxidation of low-density lipoprotein. Kaempferol-7-O-β-D-glucopyranoside possesses antioxidant activity and scavenges DPPH free radicals .
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- HY-N8220
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Flidersiachromone
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Glycosidase
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Neurological Disease
Cancer
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2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS· + free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases .
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- HY-N2907
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Wnt
Ras
Endogenous Metabolite
Bacterial
Fungal
PD-1/PD-L1
Tim3
Akt
AP-1
STAT
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Infection
Neurological Disease
Inflammation/Immunology
Cancer
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Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC50 values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .
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- HY-112482A
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Adenosine Kinase
Adenosine Receptor
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Neurological Disease
Inflammation/Immunology
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ABT-702 hydrochloride is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 hydrochloride shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 hydrochloride attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 hydrochloride shows analgesic and anti-inflammatory effects in vivo. ABT-702 hydrochloride can be used for diabetic retinopathy research .
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- HY-N7627
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- HY-P2888
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BOD
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Biochemical Assay Reagents
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Metabolic Disease
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Bilirubin oxidase (BOD) is an electrocatalyst with oxygen removal activity. Bilirubin oxidase can catalyze the oxidation of bilirubin to biliverdin. Bilirubin oxidase participates in the metabolism of porphyrins and chlorophyll, and acts as a catalyst for oxygen reduction. Bilirubin oxidase can serve as a component of a single-enzyme oxygen removal system for reductase-based voltammetric biosensors .
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- HY-N7607
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Reactive Oxygen Species (ROS)
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Cardiovascular Disease
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Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid glycoside with antioxidant activity and free radical scavenging activity. Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside can scavenge free radicals such as ABTS+ and can be used in the study of antioxidant-related diseases (such as cardiovascular diseases and neurodegenerative diseases) .
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- HY-N0435
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DNA/RNA Synthesis
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Cancer
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Isorhamnetin 3-gentiobioside is a flavonoid with activity of promoting cancer cell proliferation. Isorhamnetin 3-gentiobioside is an activator of DNA synthesis in MCF-7 human breast cancer cells with an EC50 of 3.1 μg/mL. Isorhamnetin 3-gentiobioside exhibits ABTS radical scavenging activity with an IC50 of 33.43 μg/mL. The compound can be used to study the bidirectional regulatory mechanism of cancer .
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- HY-157745
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mPEG40000-SC; mPEG40000-Succinimidyl ester
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Biochemical Assay Reagents
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Others
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m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
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- HY-N8194
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Syringetin 3-O-β-D-glucoside
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Others
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Neurological Disease
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Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .
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- HY-W101585
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Isopentyl benzoate
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Environmental Pollutants
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Inflammation/Immunology
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Isoamyl benzoate (Isopentyl benzoate) is a natural aromatic ester compound. Isoamyl benzoate exhibits free radical scavenging capabilities against DPPH and ABTS, with its IC50 values being 9.55 μg/mL and 7455.54 μM TE/g respectively. Isoamyl benzoate can be used in antioxidant research .
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- HY-N5130
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Others
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Neurological Disease
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Effusol, a phenolic constituent from Juncus effuses, exhibits potent scavenging activity for DPPH and ABTS radicals, with IC50 values of 79 μM and 2.73 μM, respectively. Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampal function against stress-induced cognitive decline .
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- HY-N0828R
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Reference Standards
Autophagy
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Inflammation/Immunology
Cancer
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Pterostilbene (Standard) is the analytical standard of Pterostilbene. This product is intended for research and analytical applications. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .
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- HY-W018643A
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Methyl (E)-ferulate
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COX
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Others
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(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS + radical scavenging activities .
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- HY-138953
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nAChR
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Neurological Disease
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Epiboxidine is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418 .
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- HY-N10985
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Drug Derivative
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Cancer
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Xanthone V1a, a derivative of Xanthone (HY-N0126), is an antioxidant that can be found in the roots of Cudrania tricuspidata and twig extracts of Maclura fruticosa. Xanthone V1a exerts cytotoxic effects against colon, hepatocellular, and gastric carcinoma cells. Xanthone V1a exhibits scavenging activitys against DPPH and ABTS. Xanthone V1a can be used for the research of colon carcinoma, hepatocellular carcinoma, and gastric carcinoma .
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- HY-149008
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Amylases
Cholinesterase (ChE)
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Inflammation/Immunology
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α-Amylase-IN-3 (Compound 4) is the inhibitor for α-Amylase, AChE and AChE with IC50s of 18.04 μM, 21.04 μM and 22.2 μM, respectively. α-Amylase-IN-3 exhibits antioxidant activity. α-Amylase-IN-3 can be used in research of diabetes and oxidative stress associated disease .
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- HY-N8955
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- HY-178935
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Amylases
Reactive Oxygen Species (ROS)
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Metabolic Disease
Inflammation/Immunology
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α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an α-amylase inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes .
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- HY-N2907R
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Wnt
Reference Standards
Ras
Endogenous Metabolite
Bacterial
Fungal
PD-1/PD-L1
Tim3
Akt
AP-1
STAT
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Infection
Neurological Disease
Inflammation/Immunology
Cancer
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Atranorin (Standard) is the analytical standard of Atranorin (HY-N2907). This product is intended for research and analytical applications. Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC50 values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .
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- HY-W207699
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Monoamine Oxidase
Amylases
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Neurological Disease
Metabolic Disease
Inflammation/Immunology
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MAO-B-IN-46 (Compound 16) is a selective hMAO-B inhibitor (IC50: 26.8 nM), with weak activity against hMAO-A (IC50: 7.2054 μM). MAO-B-IN-46 (Compound 8) also acts as an α-amylase inhibitor (IC50: 19.46 μM). MAO-B-IN-46 exhibits certain neuroprotective effects and shows no significant toxicity to human gingival fibroblasts and SH-SY5Y cells. Additionally, MAO-B-IN-46 can scavenge DPPH and ABTS free radicals, with IC50 values of 17.86 μM and 17.71 μM, respectively. MAO-B-IN-46 can be used in the research of neurodegenerative diseases such as Parkinson's disease, diabetes, and diseases related to oxidative stress resistance .
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- HY-N12291
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Others
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Others
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7,4'-Dihydroxyhomoisoflavane is a natural antioxidant. 7,4'-Dihydroxyhomoisoflavane has ABTS radical-scavenging capacity with an IC50 of 0.22 mg/mL .
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- HY-156711
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IFNAR
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Inflammation/Immunology
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Ternatumoside II is a flavonoid glycoside that can be isolated from R. crenulata. Ternatumoside II can stimulate IFN-γ expression. Ternatumoside II has radical-scavenging activities (IC50s: 260.5 μM and 320.2 μM for DPPH and ABTS) .
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- HY-149670
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Ferroptosis
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Inflammation/Immunology
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Ferroptosis-IN-3 (Compound 25) is a ferroptosis inhibitor. Ferroptosis-IN-3 inhibits RSL3-induced ferroptosis (EC50: 8.6?nM in HT-1080?cells). Ferroptosis-IN-3 scavenges DPPH and ABTS radicals (EC50: 3.94?and 6.3 μM respectively). Ferroptosis-IN-3 decreases lipid peroxidation .
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- HY-P5318
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H2O2-induced oxidative damage .
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- HY-P5317
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H2O2-induced oxidative damage .
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- HY-P5317A
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H2O2-induced oxidative damage .
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- HY-176437
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Tyrosinase
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Metabolic Disease
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Tyrosinase-IN-42 (Compound 13t) is a tyrosinase inhibitor (IC50: 1.363 µM). Tyrosinase-IN-42 exhibits anti-browning effects on fresh-cut apples. Tyrosinase-IN-42 has antioxidant activity by scavenging DPPH and ABTS free radicals (IC50: 57.90 and 45.64 µM, respectively) .
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- HY-159143
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Cholinesterase (ChE)
Cytochrome P450
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Neurological Disease
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BChE-IN-33 (compound 4r), an arylaminonaphthol derivative, is a potent butyrylcholinesterase (BChE) inhibitor with an IC50 of 14.78 µM. BChE-IN-33 also inhibits CYP2C19, CYP2C9, CYP2D6. BChE-IN-33 shows potent antioxidant activity with IC50 values of 150.48 μM, 2.56 μM and 4.61 μM by DPPH, ABTS, Ferric-phenanthroline assay, respectively. BChE-IN-33 has the potential for Alzheimer research .
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- HY-N10770
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Others
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Metabolic Disease
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5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
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- HY-N11997
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Cholinesterase (ChE)
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Neurological Disease
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Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 μg/mL and 52 μg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimer's disease, potentially restoring and enhancing memory .
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- HY-146172
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
Cancer
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Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS + scavenging activity with IC50s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells .
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- HY-157124
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Tyrosinase
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Metabolic Disease
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Tyrosinase-IN-19 (compound 9) is a competitive tyrosinase inhibitor. Tyrosinase-IN-19 has strong antioxidant activities against ROS, ABTS+, and DPPH radicals. Tyrosinase-IN-19 suppresses tyrosinase expression in a dose-dependent manner .
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- HY-N8254
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Others
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Others
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Haginin A (compound 3)can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC50 values of 9.0 μM and 37.7 μM in the ABTS system and DPPH system, respectively .
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- HY-157123
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Tyrosinase
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Metabolic Disease
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Tyrosinase-IN-18 (compound 6) is a potent tyrosinase inhibitor. Tyrosinase-IN-18 inhibits melanogenesis in B16F10 mammalian cells. Tyrosinase-IN-18 has strong antioxidant activities against ROS, ABTS +, and DPPH radicals .
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- HY-N11771
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Reactive Oxygen Species (ROS)
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Others
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Glyurallin B is a flavonoid, that can be isolated from licorice (Glycyrrhiza inflata and Glycyrrhiza uralensis). Glyurallin B shows ABTS + radical scavenging activity and the inhibitory activity on lipid peroxidation, with EC50 values of 11.9 ± 0.58 μM and 15.3 ± 1.26 μM, respectivley .
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- HY-173055
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Lipoxygenase
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Inflammation/Immunology
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Ferroleuton is a competitive, selective inhibitor for 5-lipoxygenase with an IC50 of 0.21 μM. Ferroleuton exhibits antioxidant activity in DPPH (scavenges 86% DPPH-H at 50 μM), ABTS (EC50=19.42 μM) and FRAP (EC50=3.32 μM) assays .
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- HY-138953A
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nAChR
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Neurological Disease
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Epiboxidine hydrochloride is a potent and selective neural nAChR agonist with Kis of 0.46 nM and 1.2 nM for rat and human α4β2 nAChRs, respectively. Epiboxidine hydrochloride is a methylisoxazole analog of the alkaloid Epibatidine, and is also an analog of another nAChR agonist, ABT 418 .
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- HY-168957
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MMP
Reactive Oxygen Species (ROS)
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Others
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RuDiOBn scanvages DPPH and ABTS free radicals (13.2% and 5.9% clearance at 100 μg/mL), exhibits low antioxidant activity. RuDiOBn inhibits the collagen glycation, reduces the formation of advanced glycation end products (AGEs) with an IC50 of 2.45 μg/mL. RuDiOBn enhances the proliferation and migration of fibroblasts, stimulates the synthesis of collagen, promoting the skin repair and regeneration. RuDiOBn also inhibits collagenase .
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- HY-168501
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
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Neuroprotective Agent 6 (Compound Y12) is a neuroprotective agent with antioxidant activity and capabilities in DPPH, ABTS radical scavenging. Neuroprotective Agent 6 demonstrates superior neuroprotective effects in both cellular models induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and animal models induced by transient middle cerebral artery occlusion (tMCAO). Additionally, Neuroprotective Agent 6 exhibits significant metal chelating activity towards Cu 2+ .
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- HY-162639
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Glycosidase
Cholinesterase (ChE)
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Neurological Disease
Metabolic Disease
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α-Glucosidase-IN-68 (Compound 2) is an inhibitor for α-Glucosidase, AChE, and BChE, with IC50 of 0.251, 0.774 and 0.793 μM, respectively. α-Glucosidase-IN-68 exhibits antioxidant efficacy, with IC50 of 0.69 μM and 0.02 μM, in DPPH and ABTS experiments. α-Glucosidase-IN-68 exhibits antidiabetic effect in Streptozotocin (HY-13753)-induced diabetic rat models .
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- HY-172604
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TNF Receptor
Reactive Oxygen Species (ROS)
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Neurological Disease
Inflammation/Immunology
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Neuroprotective agent 10 (Compound 11c) is a brain-penetrant neuroprotective agent. Neuroprotective agent 10 scavenges ABTS radicals (scavenging IC50: 9.20 μM), DPPH radicals (scavenging IC50: 7.09 μM) and superoxide anion radicals (inhibition percentage: 48.4%). Neuroprotective agent 10 also alleviates H2O2-induced oxidative damage and LPS-induced neuroinflammation with antiepileptic activity. Neuroprotective agent 10 is promising for research of epilepsy and neuroprotection .
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- HY-N19783
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Drug Derivative
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Others
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Carambolaside M acts as an ABTS radical cation scavenger. Carambolaside M scavenges ABTS radical cations. Carambolaside M is isolated from the fresh sweet fruits of Averrhoa carambola L., a plant belonging to the genus Averrhoa in the Oxalidaceae family .
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- HY-N18052
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Others
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Inflammation/Immunology
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Massonianoside E is an antioxidant that has been found to be present in the fruits of Viburnum rhytidophyllum Hemsl. Massonianoside E can exert antioxidant activity in DPPH, ABTS and PTIO assays .
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- HY-N18281
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Drug Derivative
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Inflammation/Immunology
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Hazelnutin F is an indoleacetic acid glycoside found in the kernels of Corylus avellana L.. Hazelnutin F lacks significant antioxidant activity against ABTS and DPPH radicals .
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- HY-N17925
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Glycosidase
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Metabolic Disease
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Falandioside B is an α-glucosidase inhibitor with an IC50 of 107.52 μM. Falandioside B scavenges ABTS radical cations. Falandioside B is applicable to research related to postprandial hyperglycemia .
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- HY-180506
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Tyrosinase
Glycosidase
Cholinesterase (ChE)
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Others
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Tyrosinase-IN-47 (compound 6a) is a potent competitive tyrosinase inhibitor with an IC50 of 1.43 µM and a Ki of 0.1142 μM. Tyrosinase-IN-47 also shows inhibition activity in α-Glucosidase (IC50 = 36.26 μM) and acetylcholinesterase (IC50 = 8.26 μM). Tyrosinase-IN-47 exhibits in vitro antioxidant activity, with good scavenging ability for DPPH (IC50 = 4.75 μM) and ABTS (IC50 = 0.04 μM). Tyrosinase-IN-47 displays anti-browning effect on freshly cut potatoes. Tyrosinase-IN-47 can be used for pharmaceutical research .
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- HY-181069
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- HY-182333
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Cholinesterase (ChE)
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Neurological Disease
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AChE-IN-112 is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.41 μM. AChE-IN-112 scavenges various reactive oxygen and reactive nitrogen species, including DPPH, ABTS, NO, hydroxyl and hydrogen peroxide free radicals. AChE-IN-112 can be used for the research of Alzheimer's disease .
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- HY-N17733
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Others
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Metabolic Disease
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4,5-O-Dicaffeoylquinic acid ethyl ester is an ABTS free radical scavenger with an IC50 of 5.95 μM. 4,5-O-Dicaffeoylquinic acid ethyl ester shows no antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. 4,5-O-Dicaffeoylquinic acid ethyl ester can be used in liver injury protection studies .
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- HY-N9229
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NO Synthase
Bacterial
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Infection
Inflammation/Immunology
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Myricadenin A is an iNOS inhibitor, capable of effectively inhibiting the production of NO (EC₅₀ = 18.1 μM). Myricadenin A has moderate ABTS free radical scavenging activity (SC₅₀ = 175.4 μM) and relatively weak anti-tuberculosis activity (MIC = 80.0 μg/mL). Myricadenin A can be used in inflammation-related research .
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- HY-181253
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Glycosidase
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Metabolic Disease
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α-Glucosidase-IN-111 (Compound 5d) is an α-glucosidase (α-Glucosidase) inhibitor with a IC50 of 34.99 μg/mL. α-Glucosidase-IN-111 effectively scavenges DPPH free radicals and ABTS free radicals, with IC50 values of 5.33 and 5.84 μg/mL, respectively. α-Glucosidase-IN-111 can be used in the research of type 2 diabetes .
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- HY-183792
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Bacterial
Reactive Oxygen Species (ROS)
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Infection
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Antibacterial agent 347 (Compound 4d) is an Antibacterial agent. Antibacterial agent 347 exhibits selective antibacterial activity against Streptococcus mutans. Antibacterial agent 347 shows moderate ABTS• + free radical scavenging activity .
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- HY-P11646
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COX
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Metabolic Disease
Inflammation/Immunology
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Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC50 of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC50 = 12.55 μM) . Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation .
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- HY-169406
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Glycosidase
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Cancer
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α-Glucosidase-IN-76 (Compound 4r) is an inhibitor for α-glucosidase with an IC50 of 5.44 μM. α-Glucosidase-IN-76 scavenges ABTS+ free radicals with a TEAC value of 0.49. α-Glucosidase-IN-76 inhibits the proliferation of T24 bladder cancer cell with IC50 of 1.74 μM .
|
-
- HY-179711
-
|
|
Cholinesterase (ChE)
Amyloid-β
|
Neurological Disease
|
|
AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 μM respectively. AChE/BChE-IN-32 inhibits Aβ aggregation and exhibits a strong ABTS•+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimer's disease .
|
-
- HY-N16424
-
|
Me cis-ferulate; cis-Ferulic acid methyl ester
|
Fungal
|
Infection
|
|
Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS + radical .
|
-
- HY-181353
-
|
|
Glycosidase
|
Metabolic Disease
Cancer
|
|
α-Glucosidase-IN-112 is an α-glucosidase inhibitor with an IC50 of 2.03 μM and a Ki of 0.44 μM. α-Glucosidase-IN-112 exerts antioxidant effects by scavenging ABTS + free radicals. α-Glucosidase-IN-112 exerts antiproliferative effects by inhibiting the proliferation of bladder cancer cells. α-Glucosidase-IN-112 can be used in research related to type 2 diabetes and bladder cancer .
|
-
- HY-181029
-
|
|
Tyrosinase
|
Neurological Disease
Inflammation/Immunology
|
|
Tyrosinase-IN-49 (Compound 12) is a potent and mixed-type chalcone-based tyrosinase inhibitor with an IC50 of 0.19 μM. Tyrosinase-IN-49 has potent antioxidant potential with significant DPPH and ABTS radical scavenging capacity. Tyrosinase-IN-49 can chelate the binuclear copper ions in the active center of tyrosinase and reduce Cu 2+ to Cu +, thereby reducing the catalytic activity of the enzyme. Tyrosinase-IN-49 has low cytotoxicity for HEK293 cells and zebrafish embryo. Tyrosinase-IN-49 shows antibrowning effects to improve food quality and can be used for research of food preservation .
|
-
- HY-181028
-
|
|
Tyrosinase
|
Neurological Disease
Inflammation/Immunology
|
|
Tyrosinase-IN-48 (Compound 3) is a potent and competitive chalcone-based tyrosinase inhibitor with an IC50 of 0.49 μM. Tyrosinase-IN-48 has potent antioxidant potential with significant DPPH and ABTS radical scavenging capacity. Tyrosinase-IN-48 can chelate the binuclear copper ions in the active center of tyrosinase and reduce Cu 2+ to Cu +, thereby reducing the catalytic activity of the enzyme. Tyrosinase-IN-48 has low cytotoxicity for HEK293 cells and zebrafish embryo. Tyrosinase-IN-48 shows antibrowning effects to improve food quality and can be used for research of food preservation .
|
-
- HY-182788
-
|
|
GSK-3
Tau Protein
Amyloid-β
β-catenin
|
Neurological Disease
|
|
Multitarget AD-IN-7 is an orally active multi-target anti-AD compound. Multitarget AD-IN-7 exhibits inhibitory activity against GSK-3β and GSK-3α (IC50 = 0.66, 0.83 nM). Multitarget AD-IN-7 upregulates the expression of p-GSK-3β-Ser9, inhibits the phosphorylation of tau-Ser396, targets Aβ1-42, chelates pathogenic metal ions, scavenges ABTS•+, upregulates the expression of β-catenin and neurogenesis biomarkers, and promotes neurite outgrowth. Multitarget AD-IN-7 improves motor ability in Alzheimer's disease zebrafish. Multitarget AD-IN-7 is applicable to research related to Alzheimer's disease .
|
-
- HY-N16851
-
-
| Cat. No. |
Product Name |
Type |
-
- HY-15902
-
|
AzBTS-(NH4)2
|
Fluorescent Dye
|
|
ABTS diammonium salt (AzBTS-(NH4)2) is a substrate for horseradish peroxidase (HRP) conjugate. ABTS diammonium salt can be used to evaluate antioxidant capacity .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5318
-
|
|
Reactive Oxygen Species (ROS)
|
Inflammation/Immunology
|
|
MDYYFEER is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER has high DPPH and ABTS radical scavenging ability. MDYYFEER protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5317
-
|
|
Reactive Oxygen Species (ROS)
|
Inflammation/Immunology
|
|
MAQAAEYYR is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5316A
-
|
|
Peptides
|
Inflammation/Immunology
|
|
MHLWAAK TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK TFA has high DPPH and ABTS radical scavenging ability. MHLWAAK TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5318A
-
|
|
Peptides
|
Inflammation/Immunology
|
|
MDYYFEER TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MDYYFEER TFA has high DPPH and ABTS radical scavenging ability. MDYYFEER TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5317A
-
|
|
Reactive Oxygen Species (ROS)
|
Inflammation/Immunology
|
|
MAQAAEYYR TFA is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MAQAAEYYR TFA has high DPPH, ABTS radical and ROS-scavenging ability. MAQAAEYYR TFA protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P5316
-
|
|
Peptides
|
Inflammation/Immunology
|
|
MHLWAAK is an antioxidant active peptide that can be isolated from pancreatin hydrolysate of C-phycocyanin. MHLWAAK has high DPPH and ABTS radical scavenging ability. MHLWAAK protects zebrafish larvae from H2O2-induced oxidative damage .
|
-
- HY-P11646
-
|
|
COX
|
Metabolic Disease
Inflammation/Immunology
|
|
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC50 of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC50 = 12.55 μM) . Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0828
-
-
-
- HY-N0778
-
-
-
- HY-W047187
-
|
|
Structural Classification
other families
Onychium japonicum (Thunb.) Kunze
Ketones, Aldehydes, Acids
Plants
|
Xanthine Oxidase
NO Synthase
TNF Receptor
|
|
Lavandoside is an ABTS ?+ free radical scavenger and a moderate inhibitor of xanthine oxidase (XO), with an IC50 of 71.6 μM for inhibiting NO production in LPS-induced macrophages. Lavandoside exerts its antioxidant and potential anti-inflammatory effects by directly scavenging free radicals and inhibiting XO activity, a mechanism related to the hydroxyl groups in its molecular structure. Lavandoside can be isolated from lavender and can be used in the development of natural antioxidants and in research on oxidative stress-related diseases and inflammation-related diseases .
|
-
-
- HY-N7005
-
-
-
- HY-N0627
-
-
-
- HY-N8220
-
-
-
- HY-N2907
-
|
|
other families
Classification of Application Fields
Phenols
Polyphenols
Plants
Endogenous metabolite
Disease Research Fields
Source Classification
Cancer
|
Wnt
Ras
Endogenous Metabolite
Bacterial
Fungal
PD-1/PD-L1
Tim3
Akt
AP-1
STAT
|
|
Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC50 values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .
|
-
-
- HY-N7627
-
-
-
- HY-N7607
-
-
-
- HY-N0435
-
-
-
- HY-N8194
-
-
-
- HY-N5130
-
-
-
- HY-N0828R
-
|
|
Structural Classification
Monophenols
other families
Stilbenes
Phenols
Plants
Source Classification
|
Reference Standards
Autophagy
|
|
Pterostilbene (Standard) is the analytical standard of Pterostilbene. This product is intended for research and analytical applications. Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .
|
-
-
- HY-W018643A
-
-
-
- HY-N10985
-
-
-
- HY-N8955
-
-
-
- HY-N2907R
-
|
|
Structural Classification
other families
Phenols
Polyphenols
Plants
Endogenous metabolite
Source Classification
|
Wnt
Reference Standards
Ras
Endogenous Metabolite
Bacterial
Fungal
PD-1/PD-L1
Tim3
Akt
AP-1
STAT
|
|
Atranorin (Standard) is the analytical standard of Atranorin (HY-N2907). This product is intended for research and analytical applications. Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC50 values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions .
|
-
-
- HY-N12291
-
-
-
- HY-156711
-
-
-
- HY-N10770
-
|
|
Flavonoids
Gramineae
Plants
Other Flavonoids
Saccharum officinarum
Source Classification
|
Others
|
|
5'-Geranyl-5,7,2',4'-tetrahydroxyflavone, a phenolic compound, presents strong oxygen radical absorbance capacity (ORAC), DPPH radical-scavenging capacity, ABTS radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. 5'-Geranyl-5,7,2',4'-tetrahydroxyflavone has the potential for natural antioxidant research .
|
-
-
- HY-N11997
-
|
|
Liliaceae
Coumarins
Phenols
Polyphenols
Aloe vera (L.) Burm. f.
Phenylpropanoids
Plants
Source Classification
|
Cholinesterase (ChE)
|
|
Feralolide is a dihydroisocoumarin isolated from the methanolic extract of aloe vera resin. Feralolide is also a dual inhibitor of AChE and BuChE, with IC50s of 55 μg/mL and 52 μg/mL respectively. Feralolide has antioxidant activity and inhibits 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Feralolide could be used in research into cognitive disorders such as Alzheimer's disease, potentially restoring and enhancing memory .
|
-
-
- HY-N8254
-
-
-
- HY-N11771
-
-
-
- HY-N19783
-
-
-
- HY-N18052
-
-
-
- HY-N18281
-
-
-
- HY-N17925
-
-
-
- HY-N17733
-
-
-
- HY-N9229
-
-
-
- HY-N16424
-
|
Me cis-ferulate; cis-Ferulic acid methyl ester
|
Monophenols
Phenols
Aizoaceae
Plants
Tetragonia tetragonioides (Pall.) Kuntze
Source Classification
|
Fungal
|
|
Methyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS + radical .
|
-
-
- HY-N16851
-
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-157745
-
|
mPEG40000-SC; mPEG40000-Succinimidyl ester
|
|
Polymers
|
|
m-PEG-NHS ester (mPEG-SC; mPEG-Succinimidyl ester) (MW 40000) is a polyethylene glycol derivative. m-PEG-NHS ester serves as a modifying agent that reacts with free amino groups on the surface of protein or polypeptide molecules to form stable amide bonds, thereby covalently linking PEG chains to biomacromolecules, improving their antigenicity and immunogenicity, and facilitating the preparation of injectable formulations .
|
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