17429-69-5
Chemical Structure
Isorhamnetin 3-gentiobioside
- CAS No.: 17429-69-5
- Formula:C28H32O17
- Molecular Weight:640.54
IUPAC Name: 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: GPZLFWVUSQREQH-QDYVESOYSA-N
SMILES: OC1=CC=C(C(OC2=C3C(O)=CC(O)=C2)=C(O[C@@H]4O[C@H](CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)C3=O)C=C1OC
Biological Activity: Isorhamnetin 3-gentiobioside is a flavonoid with activity of promoting cancer cell proliferation. Isorhamnetin 3-gentiobioside is an activator of DNA synthesis in MCF-7 human breast cancer cells with an EC50 of 3.1 μg/mL. Isorhamnetin 3-gentiobioside exhibits ABTS radical scavenging activity with an IC50 of 33.43 μg/mL. The compound can be used to study the bidirectional regulatory mechanism of cancer[1][2].
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Isorhamnetin 3-gentiobioside | 99.69% | Isorhamnetin 3-gentiobioside is a flavonoid with activity of promoting cancer cell proliferation. Isorhamnetin 3-gentiobioside is an activator of DNA synthesis in MCF-7 human breast cancer cells with an EC50 of 3.1 μg/mL. Isorhamnetin 3-gentiobioside exhibits ABTS radical scavenging activity with an IC50 of 33.43 μg/mL. The compound can be used to study the bidirectional regulatory mechanism of cancer. | ||||||||||||||||||||
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- [1]. Yang C , Yang Y , Akber A H , et al. Bioassay-guided isolation of antioxidants from Astragalus altaicus by combination of chromatographic techniques[J]. Journal of Separation ence, 2015, 35(8):977-983. [Content Brief]
- [2]. Ninfali P, et al. Characterization and biological activity of the main flavonoids from Swiss Chard (Beta vulgaris subspecies cycla). Phytomedicine. 2007 Feb;14(2-3):216-21. [Content Brief]
Keywords
