Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside

Name: Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside
Brand: MedChemExpress
SKU: HY-N7607
Rating: 4.5 (0 reviews)

製品番号: HY-N7607 純度: 99.87%: Data Sheet SDS COA 取扱説明書
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Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside is a flavonoid glycoside with antioxidant activity and free radical scavenging activity. Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside can scavenge free radicals such as ABTS+ and can be used in the study of antioxidant-related diseases (such as cardiovascular diseases and neurodegenerative diseases).

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Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside 構造式

CAS 番号 : 143016-74-4

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 128	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 128	在庫あり	Estimated Time of Arrival: December 31
Solid
1 mg	$50	在庫あり	Estimated Time of Arrival: December 31
5 mg	$95	在庫あり	Estimated Time of Arrival: December 31
10 mg	$135	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

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Based on 0 publication(s) in Google Scholar

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純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

体外実験

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside (5-160 μg/mL) exhibits concentration-dependent targeted ABTS⁺ radical scavenging activity, with MDL at 0.07 μg/mL and MQL at 0.2 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

610.52

分子式

C₂₇H₃₀O₁₆

CAS 番号

143016-74-4

Appearance

Solid

Color

White to yellow

SMILES

O=C1C(O[C@H](O[C@H]2C)[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO)=C(C(C=C4)=CC(O)=C4O)OC5=CC(O)=CC(O)=C15

Structure Classification

Initial Source

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (163.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 14.29 mg/mL (23.41 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6379 mL	8.1897 mL	16.3795 mL
5 mM	0.3276 mL	1.6379 mL	3.2759 mL
10 mM	0.1638 mL	0.8190 mL	1.6379 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 2.5 mg/mL (4.09 mM); Clear solution; Need ultrasonic

This protocol yields a clear solution of 2.5 mg/mL.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (4.09 mM); Clear solution; Need ultrasonic

This protocol yields a clear solution of 2.5 mg/mL.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (4.09 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

純度とドキュメンテーション

純度: 99.87%

Select Batch:

データシート (279 KB) SDS (252 KB)

COA (270 KB) HNMR (302 KB) LCMS (97 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Huifen Ma, et al. A powerful on line ABTS +-CE-DAD method to screen and quantify major antioxidants for quality control of Shuxuening Injection. Sci Rep. 2018 Apr 3;8(1):5441. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	1.6379 mL	8.1897 mL	16.3795 mL	40.9487 mL
	5 mM	0.3276 mL	1.6379 mL	3.2759 mL	8.1897 mL
	10 mM	0.1638 mL	0.8190 mL	1.6379 mL	4.0949 mL
	15 mM	0.1092 mL	0.5460 mL	1.0920 mL	2.7299 mL
	20 mM	0.0819 mL	0.4095 mL	0.8190 mL	2.0474 mL
DMSO	25 mM	0.0655 mL	0.3276 mL	0.6552 mL	1.6379 mL
	30 mM	0.0546 mL	0.2730 mL	0.5460 mL	1.3650 mL
	40 mM	0.0409 mL	0.2047 mL	0.4095 mL	1.0237 mL
	50 mM	0.0328 mL	0.1638 mL	0.3276 mL	0.8190 mL
	60 mM	0.0273 mL	0.1365 mL	0.2730 mL	0.6825 mL
	80 mM	0.0205 mL	0.1024 mL	0.2047 mL	0.5119 mL
	100 mM	0.0164 mL	0.0819 mL	0.1638 mL	0.4095 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.