1 Result for "

APJ receptor agonist5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "APJ receptor agonist5" in MCE Product Catalog:

Cat. No.: HY-145285
CAS No.: 2135514-20-2
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease .
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