1 Result for "

APWR-centered alternative activation motif

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "APWR-centered alternative activation motif" in MCE Product Catalog:

Cat. No.: HY-P12217
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease

Cyclic MC4R peptide agonist-1 is a cyclic peptide agonist of the melanocortin-4 receptor (melanocortin-4 receptor). Cyclic MC4R peptide agonist-1 activates the human melanocortin-4 receptor via an alternative activation motif centered on APWR, and this activation process is independent of the classical HFRW pharmacophore. Cyclic MC4R peptide agonist-1 inhibits signal transduction of the human melanocortin-3 receptor and melanocortin-5 receptor. Cyclic MC4R peptide agonist-1 is used in research related to obesity .
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