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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1281 Results for "
Acetyl
" in MedChemExpress (MCE) Product Catalog:
Products (1281)
1281 Results for "Acetyl" in MCE Product Catalog:
735
735 Publications Verification
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
698
698 Cited Publications
Synonyms: Hydroxydaunorubicin hydrochloride; ADR
145
47
47 Cited Publications
Cat. No.: HY-P1001
CAS No.: 169332-60-9
42
42 Cited Publications
Cat. No.: HY-D0989
CAS No.: 145037-81-6
24
24 Cited Publications
Cat. No.: HY-16901
CAS No.: 1434635-54-7
Synonyms: ND-630; GS-0976; NDI-010976
Target:
Domaines de recherche:
Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.
18
18 Cited Publications
BAY-3827, a chemical probe, is a potent and selective AMPK inhibitor with IC50 values of 1.4 nM at low (10 μM ATP concentration) and 15 nM at high (2 mM ATP concentration). BAY-3827 shows over 500-fold selectivity for most of the 331 kinases. BAY-3827 prevents phosphorylation of acetyl-CoA carboxylase 1 and shows strongest anti-proliferative activity in androgen-dependent prostate cancer cell lines .
14
14 Cited Publications
Target:
Domaines de recherche:
ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
13
13 Cited Publications
Synonyms: N-Acetylcysteine ethyl ester; NACET
Target:
Domaines de recherche:
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .
13
13 Cited Publications
Cat. No.: HY-P1005
CAS No.: 201608-14-2
Target:
Domaines de recherche:
11
11 Cited Publications
Synonyms: RMI14514; MDL14514
Target:
Domaines de recherche:
TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ).
11
11 Cited Publications
Target:
Domaines de recherche:
CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation .
11
11 Cited Publications
Target:
Domaines de recherche:
CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation .
11
Target:
Domaines de recherche:
Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist .
11
11 Cited Publications
Target:
Domaines de recherche:
WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice .
10
10 Cited Publications
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Other Diseases Endogenous metabolite Disease Research Fields
Target:
8
8 Cited Publications
Cat. No.: HY-B2244
CAS No.: 206658-92-6
Target:
Domaines de recherche:
Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
8
8 Cited Publications
Synonyms: 1-NaphthylAcetyl spermine
Target:
Domaines de recherche:
Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
8
8 Cited Publications
Target:
Domaines de recherche:
Ac-CoA Synthase-IN-1 is a potent, reversible acetate-dependent acetyl-CoA synthetase 2 (ACSS2) inhibitor with an IC50 of 0.6 μM . Ac-CoA Synthase-IN-1 inhibits the respiratory syncytial virus (RSV) .
7
7 Cited Publications
Synonyms: Acetyl-CoA trisodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
