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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Actin bundling
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Actin bundling" in MCE Product Catalog:
Research Areas:
Gamendazole, an indazole carboxylic acid (ICA), is an orally active, selective HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A) inhibitor. Gamendazole binds to the C-terminal nucleotide binding pocket of HSP90 and cause downregulation of clients AKT1 and ERBB2, but stabilizes the HSP90 heterocomplex. Gamendazole specifically inhibits the actin bundling function of EEF1A1, but does not bind to the nucleotide docking pocket nor inhibits the ribosome charging or protein translation functions of EEF1A1. Gamendazole, an antispermatogenic compound with antifertility effects, has the potential for reversible non-hormonal male contraceptive agent research .
Cat. No.: HY-N6701
CAS No.: 39156-67-7
Research Areas:
Dihydrocytochalasin B is an Actin disruptor. Dihydrocytochalasin B disrupts actin microfilament bundles, inhibits actin polymerization, and alters intracellular actin cytoskeletal structures. Dihydrocytochalasin B blocks the initiation of DNA synthesis. Dihydrocytochalasin B inhibits Calcium transport. Dihydrocytochalasin B inhibits cytokinesis and alters cell morphology. Dihydrocytochalasin B can be used in studies related to rickets .
Cat. No.: HY-175753
CAS No.: 2094958-44-6
Z17544625 is a Fascin inhibitor. Z17544625 has a strong binding capacity to fascin and inhibits Actin bundling. Z17544625 significantly reduces proliferation and impairs migration of CRC cells. Z17544625 can be used for cancer, especially colorectal cancer (CRC) research .
Cat. No.: HY-175762
Z118298144 is a Fascin inhibitor. Z118298144 has a strong binding capacity to fascin and inhibits Actin bundling. Z118298144 significantly reduces proliferation and impairs migration of CRC cells. Z118298144 can be used for cancer, especially colorectal cancer (CRC) research .
Cat. No.: HY-187686
CAS No.: 2606843-12-1
Target:
Research Areas:
UA49 is a plasma membrane voltage-dependent potassium channel inhibitor. UA49 inhibits the phosphorylation of plasma membrane H +-ATPase, reduces potassium ion levels in guard cells, increases calcium ion concentrations in the cytoplasm and endoplasmic reticulum, induces actin filament bundling, and triggers SLAC1-dependent stomatal closure through a pathway distinct from that of ABA. UA49 can be used in studies related to plant drought stress .
Cat. No.: HY-P85913
Synonyms: 55 kDa Actin bundling protein; 55 kDa Actin-bundling protein; Actin bundling protein; Actin bundling protein, 55-KD; FAN 1; FAN1; Fascin 1; Fascin Actin bundling protein 1; Fascin; Fascin homolog 1 Actin bundling protein; Strongylocentrotus purpuRatus; Fascin homolog 1; Fascin, sea urchin, homolog of, 1; Fascin1; FLJ38511; FSCN 1; FSCN1; FSCN1_HUMAN; HSN; p55; Singed; Drosophila; like; sea urchin fascin homolog like; Singed drosophila homolog like; Singed like; fascin homolog sea urchin; Drosophila; Singed like; fascin homolog sea urchin; Singed like protein; Singed, drosophila, homolog of; Singed-like protein; SNL; Strongylocentrotus purpuRatus
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
