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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Akt 2 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Akt 2 kinase" in MCE Product Catalog:
91
91 Publications Verification
Synonyms: AZD5363
Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
42
42 Cited Publications
GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
20
20 Cited Publications
Synonyms: GSK2110183; LAE002
Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively .
20
20 Cited Publications
Synonyms: GSK2110183 hydrochloride; LAE002 hydrochloride
Afuresertib hydrochloride (GSK 2110183 hydrochloride) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively .
7
7 Cited Publications
CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC50=6 nM for AKT2). CCT128930 has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). Antitumor activity.
3
3 Cited Publications
Cat. No.: HY-P86312
Synonyms: Akt antibody;
Akt1 antibody;
Akt1 kinase antibody;
Akt1m antibody;
Akt2 antibody;
Akt2 kinase antibody;
Akt3 antibody;
Akt3_HUMAN antibody;
CAkt antibody;
CWS6 antibody;
DKFZp434N0250 antibody;
HIHGHH antibody;
kinase Akt1 antibody;
MGC99656 antibody;
MPPH antibody;
Murine thymoma viral (v-Akt) homolog 2 antibody;
pan-Akt antibody
2
Target:
Research Areas:
Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor against AKT1 (IC50=0.55 nM), AKT2 (IC50=0.81 nM), and AKT3 (IC50=1.31 nM). Vevorisertib, as a single agent or in combination with other anti-cancer agents, can be used for the research of solid tumors with PIK3CA / AKT / PTEN mutations .
1
1 Cited Publications
Cat. No.: HY-P74420
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Akt2; Non-Specific Serine/Threonine Protein kinase; Akt Serine/Threonine kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein kinase Beta; RAC-Beta Serine/Threonine-Protein kinase; RAC Protein kinase Beta; Protein kinase B Beta; Akt2 Protein; Protein kinase Akt-2; RAC-BETA; RAC-PK-Beta; PKBBETA; PKB Beta; HIHGHH; PKBB; PRKBB; Putative V-Akt Murine Thymoma Viral Oncoprotein 2; PKBβ
Species:
Human
Source:
Sf9 insect cells
Category:
Target:
AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells .
Cat. No.: HY-15431R
CAS No.: 1143532-39-1
Synonyms: AZD5363 (Standard)
Target:
Research Areas:
Capivasertib (Standard) is the analytical standard of Capivasertib. This product is intended for research and analytical applications. Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
Cat. No.: HY-E70791
AKT is the oncogenic protein kinase that regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Mammalian cells are characterized by the expression of three different Akt isoforms, Akt1, Akt2, and Akt3. Biotin-AKT2 Recombinant Human Active Protein Kinase is obtained by expressing AKT2 proteins and is biotinylated .
Cat. No.: HY-E70786
AKT is the oncogenic protein kinase that regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Mammalian cells are characterized by the expression of three different Akt isoforms, Akt1, Akt2, and Akt3. AKT1 E17K is a mutant of AKT1. AKT1 E17K Recombinant Human Active Protein Kinase is obtained by expressing AKT1 E17K proteins .
Cat. No.: HY-P702632
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Akt2; Non-Specific Serine/Threonine Protein kinase; Akt Serine/Threonine kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein kinase Beta; RAC-Beta Serine/Threonine-Protein kinase; RAC Protein kinase Beta; Protein kinase B Beta; Akt2 Protein; Protein kinase Akt-2; RAC-BETA; RAC-PK-Beta; PKBBETA; PKB Beta; HIHGHH; PKBB; PRKBB; Putative V-Akt Murine Thymoma Viral Oncoprotein 2; PKBβ
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706017
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Akt2; Non-Specific Serine/Threonine Protein kinase; Akt Serine/Threonine kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein kinase Beta; RAC-Beta Serine/Threonine-Protein kinase; RAC Protein kinase Beta; Protein kinase B Beta; Akt2 Protein; Protein kinase Akt-2; RAC-BETA; RAC-PK-Beta; PKBBETA; PKB Beta; HIHGHH; PKBB; PRKBB; Putative V-Akt Murine Thymoma Viral Oncoprotein 2; PKBβ
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702854
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Akt2; Non-Specific Serine/Threonine Protein kinase; Akt Serine/Threonine kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein kinase Beta; RAC-Beta Serine/Threonine-Protein kinase; RAC Protein kinase
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P705728
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Akt2; Non-Specific Serine/Threonine Protein kinase; Akt Serine/Threonine kinase 2; Murine Thymoma Viral (V-Akt) Homolog-2; V-Akt Murine Thymoma Viral Oncogene Homolog 2; Rac Protein kinase Beta; RAC-Beta Serine/Threonine-Protein kinase; RAC Protein kinase
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P86450
Synonyms: Akt antibody; Akt1 antibody; Akt1 kinase antibody; Akt1m antibody; Akt2 antibody; Akt2 kinase antibody; Akt3 antibody; Akt3_HUMAN antibody; CAkt antibody; CWS6 antibody; DKFZp434N0250 antibody; HIHGHH antibody; kinase Akt1 antibody; MGC99656 antibody; MPPH antibody; Murine thymoma viral (v-Akt) homolog 2 antibody; pan-Akt antibody
Cat. No.: HY-E70792
AKT is the oncogenic protein kinase that regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Mammalian cells are characterized by the expression of three different Akt isoforms, Akt1, Akt2, and Akt3. Biotin-AKT3 Recombinant Human Active Protein Kinase is obtained by expressing AKT3 proteins and is biotinylated .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
