1143532-39-1
Chemical Structure
Capivasertib
Synonym(s): AZD5363
- CAS No.: 1143532-39-1
- Formula:C21H25ClN6O2
- Molecular Weight:428.92
IUPAC Name: (S)-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
InChIKey: JDUBGYFRJFOXQC-KRWDZBQOSA-N
SMILES: O=C(C1(N)CCN(C2=C3C(NC=C3)=NC=N2)CC1)N[C@H](C4=CC=C(Cl)C=C4)CCO
Biological Activity: Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
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Capivasertib | 99.96% | Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively. | ||||||||||||||||||||
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Capivasertib (Standard) | ≥98% | Capivasertib (Standard) is the analytical standard of Capivasertib. This product is intended for research and analytical applications. Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively. | ||||||||||||||||||||
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Capivasertib-d4 | Capivasertib-d4 (AZd5363-d4) is the deuterium labeled Capivasertib (HY-15431). Capivasertib (AZD5363) is an orally active and potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively. | |||||||||||||||||||||
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