1 Result for "

Akt1-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Akt1-IN-8" in MCE Product Catalog:

Cat. No.: HY-173122
CAS No.: 2247688-87-3
Target:  

Akt

Research Areas:  

Cancer

Akt1-IN-8 (Compound JL18) is a potent and oral bioavailable (41%) inhibitor of AKT1 kinase, with an IC50 of 8.8 nM. Akt1-IN-8 exhibits significant antiproliferative effects against PC-3 prostate cancer cells, with an IC50 of 3.0 μM. Akt1-IN-8 can reduce phosphorylated GSK3β levels .
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