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Akt1-IN-8

Akt1-IN-8 (Compound JL18) is a potent and oral bioavailable (41%) inhibitor of AKT1 kinase, with an IC50 of 8.8 nM. Akt1-IN-8 exhibits significant antiproliferative effects against PC-3 prostate cancer cells, with an IC50 of 3.0 μM. Akt1-IN-8 can reduce phosphorylated GSK3β levels.

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  • CAS 番号: 2247688-87-3
  • 分子式: C21H25Br2N7O
  • 分子量:551.28
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Akt1-IN-8 Chemical Structure
    Akt1-IN-8 構造式
CAS 番号: 2247688-87-3
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  • Akt1-IN-8 Chemical Structure
    Akt1-IN-8 Chemical Structure
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  • Akt1-IN-8