1 Result for "

BPN-15606 besylate

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BPN-15606 besylate" in MCE Product Catalog:

Cat. No.: HY-117482A
CAS No.: 2436239-00-6
Target:  

γ-secretase

Research Areas:  

Neurological Disease

BPN-15606 besylate is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. BPN-15606 besylate lowers Aβ42 and Aβ40 levels in the central nervous system of rats and mice. BPN-15606 besylate has acceptable PK/PD properties, including bioavailability, half-life, and clearance .
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