344 Results for "

Bacillus

" in MedChemExpress (MCE) Product Catalog:
Products (344)

344 Results for "Bacillus" in MCE Product Catalog:

427
427 Publications Verification
Cat. No.: HY-12028
CAS No.: 167869-21-8
Purity:  98.89%
Research Areas:  

Cancer

PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM). PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG)-induced autophagy .
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8
8 Cited Publications
Cat. No.: HY-17586
CAS No.: 2227366-51-8
Synonyms: MDL-63397 hydrochloride; BI-397 hydrochloride
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
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8
8 Cited Publications
Cat. No.: HY-17586A
CAS No.: 171500-79-1
Synonyms: MDL-63397; BI-397
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Dalbavancin (MDL-63397) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively .
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3
3 Cited Publications
Cat. No.: HY-P1748
CAS No.: 9073-78-3
Synonyms: EC 3.4.24.27; TML
Research Areas:  

Others

Thermolysin, Bacillus thermoproteolyticus rokko (EC 3.4.24.27) (TML) is a thermostable neutral metalloproteinase enzyme secreted by the Gram-positive bacteria Bacillus thermoproteolyticus. Thermolysin catalyzes the hydrolysis of peptide bonds containing hydrophobic residues .

Optimal pH: 8.0. Considerably stable from pH 5 to 9.5.
Optimal temperature : 70 °C
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3
3 Cited Publications
Cat. No.: HY-N10473
CAS No.: 957-86-8
Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe 3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries .
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2
2 Cited Publications
Cat. No.: HY-101399
CAS No.: 7432-24-8
Purity:  99.82%
Synonyms: H-γ-Glu-Phe-OH; γ-Glutamylphenylalanine
γ-Glu-Phe is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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2
2 Cited Publications
Cat. No.: HY-101399A
CAS No.: 2828432-42-2
Purity:  99.50%
Synonyms: H-γ-Glu-Phe-OH TFA; γ-Glutamylphenylalanine TFA
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe TFA or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .
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2
2 Cited Publications
Cat. No.: HY-B0914
CAS No.: 112-38-9
Synonyms: Undecylenic acid
10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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2
2 Cited Publications
Cat. No.: HY-B0914A
CAS No.: 557-08-4
Synonyms: Zinc undecylenate
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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1
1 Cited Publications
Cat. No.: HY-P2861
CAS No.: 9029-22-5
Synonyms: SAO
Research Areas:  

Others

Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H2O2, 5,10-CH2-tetrahydrofolate, which are often used in biochemical reactions .
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1
1 Cited Publications
Cat. No.: HY-N8537
CAS No.: 260979-95-1
Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus) and does not inhibit the growth of Bacillus subtilis .
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1
1 Cited Publications
Cat. No.: HY-121497
CAS No.: 5813-86-5
Purity:  99.40%
Synonyms: 3-MBA
Target:  

PARP Bacterial

Research Areas:  

Cancer

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells . 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum) .
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1
1 Cited Publications
Cat. No.: HY-N1916
CAS No.: 63644-62-2
Coniferyl ferulate is an orally active phenolic acid compound. Coniferyl ferulate is a potent inhibitor of glutathione S-transferase (GST) (IC50 = 0.3 μM), which downregulates P-gp expression, induces apoptosis in B-MD-C1 (ADR+/+) cells, and reverses multidrug resistance. Coniferyl ferulate blocks the NMDAR/NR2B-CaMKII-MAPKs signaling pathway, inhibits ROS production and mitochondrial apoptosis, while reshapes the intestinal microbiota and microbial metabolism, ameliorates colonic inflammation and alleviates depressive symptoms in mice. Coniferyl ferulate can alleviate the toxicity of xylene to hematopoietic stem and progenitor cells by targeting Mgst2. Coniferyl ferulate exhibits antibacterial activity against the Gram-positive Bacillus subtilis and Staphylococcus aureus .
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1
1 Cited Publications
Cat. No.: HY-N11077
CAS No.: 89886-30-6
Synonyms: 4,5-di-O-CQA
4,5-Di-O-caffeoylquinic acid (4,5-di-O-CQA) is a natural product with multiple activities including anti-inflammatory, antioxidant, and antibacterial properties. 4,5-Di-O-caffeoylquinic acid induces intracellular Ca 2+ influx, and inhibits hypoxia-induced COX-2 expression and cell migration via the TRPV1-mediated pathway. 4,5-Di-O-caffeoylquinic acid scavenges DPPH free radicals, inhibits Cu 2+-mediated LDL oxidation, and reduces the production of TBARS. 4,5-Di-O-caffeoylquinic acid promotes intracellular ATP production, inhibits Aβ42 aggregation and β-sheet conversion, and protects neuroblastoma cells. 4,5-Di-O-caffeoylquinic acid inhibits the growth of Bacillus shigae. 4,5-Di-O-caffeoylquinic acid can be used in studies related to atherosclerosis, Alzheimer's disease, and bacterial infections .
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Cat. No.: HY-E70076
CAS No.: 9014-01-1
Synonyms: Bacillopeptidaseb
Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

Subtilisin, bacillus licheniformis (Bacillopeptidaseb) is a serine endopeptidase that cleaves peptide bonds with broad substrate specificity. Subtilisin, bacillus licheniformis exhibits P1 site preference (the first residue at the N-terminus of the cleavage site). Subtilisin, bacillus licheniformis can be used in protein hydrolysis, detergents, proteomics, and other fields .
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Cat. No.: HY-P2802A
CAS No.: 9001-42-7
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

α-Glucosidase, bacillus stearothermophilus is a carbohydrase enzyme that catalyzes the release of α-glucose molecules. α-Glucosidase, bacillus stearothermophilus retains exoglycosidases, which hydrolyze α-glucosidic linkage at the nonreducing end of a substrate .
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Cat. No.: HY-N13668
CAS No.: 468757-69-9
Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections .
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Cat. No.: HY-125863C
CAS No.: 9001-40-5
Synonyms: G6PD, Bacillus sp.
Research Areas:  

Metabolic Disease

Glucose-6-phosphate dehydrogenase, Bacillus sp. (G6PD, Bacillus sp.) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase, Bacillus sp. is induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl in Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. is used in research related to diabetic complications .
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Cat. No.: HY-P2936A
CAS No.: 9031-54-3
Sphingomyelin phosphodiesterase, Bacillus cereus is a sphingomyelin hydrolase and Insecticide. Sphingomyelin phosphodiesterase, Bacillus cereus catalyzes the decomposition of sphingomyelin into ceramide and phosphorylcholine. Sphingomyelin phosphodiesterase, Bacillus cereus causes rapid paralysis and death in injected insects, including German cockroaches and black cutworms. Sphingomyelin phosphodiesterase, Bacillus cereus reduces H2O2 production. Sphingomyelin phosphodiesterase, Bacillus cereus can be used in studies related to sepsis and endophthalmitis .
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Cat. No.: HY-E70284
Research Areas:  

Others

Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .
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