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Bafilomycin A1 (Standard)

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Bafilomycin A1 (Standard)
Bafilomycin A1 (Standard)
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Cat. No.: HY-100558R
CAS No.: 88899-55-2
Synonyms: BafA1 (Standard)
Category:  

Microorganisms Macrolide Antibiotics Antibiotics Disease Research Anticancer

Target:  

Reference Standards Proton Pump Autophagy Antibiotic Bacterial Apoptosis

Bafilomycin A1 (Standard) is the analytical standard of Bafilomycin A1 (HY-100558). This product is intended for research and analytical applications. Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H +-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg. Bafilomycin A1, a macrolide antibiotic, is also used as an autophagy inhibitor at the late stage. Bafilomycin A1 blocks autophagosome-lysosome fusion and inhibits acidification and protein degradation in lysosomes of cultured cells. Bafilomycin A1 induces apoptosis .
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