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2 Results for "
Bosentan hydrate (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Bosentan hydrate (Standard)" in MCE Product Catalog:
Cat. No.: HY-A0013AR
CAS No.: 157212-55-0
Research Areas:
Bosentan (hydrate) (Standard) is the analytical standard of Bosentan (hydrate). This product is intended for research and analytical applications. Bosentan hydrate is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
Cat. No.: HY-106994AR
CAS No.: 342005-82-7
Synonyms: YM598 (Standard)
Research Areas:
Nebentan potassium (Standard) (GT-2331 maleate (Standard)) is the analytical standard of Nebentan (potassium) (HY-106994A). This product is intended for research and analytical applications. Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively . YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo .
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Protocols
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