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Bugula neritina

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Endogenous Metabolite (1) HIV (1) PKC (1)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Bryostatin 1 2 Publications Verification	PKC HIV Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with K_is of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties .

Micromarin F	Others	Others
Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC₅₀ values of 10.93 and 12.38 μM .

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol	Endogenous Metabolite	Cancer
(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC₅₀ value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma .

Bryostatin 1 2 Publications Verification	Anti-inflammation/Immunoregulatory Neurological Disease Classification of Application Fields Marine natural products Other marine organisms Disease Research Infection Macrolide Antibiotics Animals Antibiotics Anticancer Inflammation/Immunology Disease Research Fields Source Classification	PKC HIV Bacterial
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with K_is of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties .

Micromarin F	Structural Classification Carlina acaulis L. Coumarins Phenylpropanoids Umbelliferae Plants Source Classification	Others
Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC₅₀ values of 10.93 and 12.38 μM .

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol	Structural Classification Tetracyclic Triterpenoids Animals Terpenoids Source Classification	Endogenous Metabolite
(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC₅₀ value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma .

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