2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC50 value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma.

For research use only. We do not sell to patients.

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol Chemical Structure

CAS No. : 1646619-90-0

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(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol Related Antibodies

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Description

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC50 value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma[1].

In Vitro

(23S,24R)-Dimethylcholest-7-ene-3β,5α,6β-triol (compound 3) (72 h) exhibits weak cytotoxicity against HepG2 (IC50 >449 μM) and SGC7901 (IC50 111.8 μM) cell lines and no activity against NCI-H460 cell line[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol Related Antibodies
Molecular Weight

446.71

Formula

C29H50O3
CAS No.
SMILES

C[C@@]12[C@]3([H])C([C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)C[C@H](C)[C@H](C)C(C)C)C)=C[C@H]([C@]1(C[C@H](CC2)O)O)O
Structure Classification
Initial Source

marine bryozoan Bugula neritina
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol1646619-90-0Endogenous MetaboliteBugula neritinaHepG2SGC7901hepatocellular carcinomahuman hepatocellular carcinoma cellsNCI-H460human lung carcinoma cellsgastric carcinomahuman gastric carcinoma cellsInhibitorinhibitorinhibit

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