(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol
(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC50 value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 1646619-90-0
- Formula: C29H50O3
- Molecular Weight:446.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
(23S,24R)-Dimethylcholest-7-ene-3β,5α,6β-triol (compound 3) (72 h) exhibits weak cytotoxicity against HepG2 (IC50 >449 μM) and SGC7901 (IC50 111.8 μM) cell lines and no activity against NCI-H460 cell line[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1646619-90-0
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Molecular Weight 446.71
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Formula C29H50O3
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SMILES
C[C@@]12[C@]3([H])C([C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)C[C@H](C)[C@H](C)C(C)C)C)=C[C@H]([C@]1(C[C@H](CC2)O)O)O
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Structure Classification
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Initial Source
marine bryozoan Bugula neritina
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)