1 Result for "

C1s-C1r-C1r-C1s/MASPs

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "C1s-C1r-C1r-C1s/MASPs" in MCE Product Catalog:

Cat. No.: HY-P10827
CAS No.: 1356469-36-7
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM .
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