65 Results for "

CD47 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (65)

65 Results for "CD47 Antibody" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P99029
CAS No.: 2169232-81-7
Synonyms: Hu5F9-G4

Target:  

CD47

Research Areas:  

Cancer

Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab, an IgG4 isotype, lacks ADCC function and exhibits relatively weak ADCP effector function. Magrolimab can be used for the study of malignant bone tumors and breast cancer .
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2
2 Cited Publications
Cat. No.: HY-P990131

Target:  

CD47

Anti-Mouse CD47/IAP Antibody (MIAP301) is an anti-mouse CD47/IAP IgG2a monoclonal antibody. Anti-Mouse CD47/IAP Antibody (MIAP301) can effectively block CD47 signaling and enhance macrophage phagocytic function. Anti-Mouse CD47/IAP Antibody (MIAP301) can increase the infiltration of immune cells. Anti-Mouse CD47/IAP Antibody (MIAP301) restores the phagocytic function of myeloid cells and alleviate B cell inhibition. Anti-Mouse CD47/IAP Antibody (MIAP301) may interfere with wound healing. Anti-Mouse CD47/IAP Antibody (MIAP301) can be used for researches on cancer, inflammation and infection conditions such as melanoma, intestinal mucosal repair and sepsis .
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1
1 Cited Publications
Cat. No.: HY-P99706
CAS No.: 2428381-55-7
Synonyms: AK 117

Research Areas:  

Cancer

Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody. Ligufalimab does not induce RBC hemagglutination, and induces phagocytosis. Ligufalimab shows anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-P99533
CAS No.: 2249722-58-3
Synonyms: SRF-231; SRF231

Research Areas:  

Cancer

Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .
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1
1 Cited Publications
Cat. No.: HY-P99026
CAS No.: 2377483-71-9
Synonyms: TJ011133; TJC4

Target:  

CD47

Research Areas:  

Cancer

Lemzoparlimab (TJ011133; TJC4) is a humanized anti-CD47 IgG4 antibody. Lemzoparlimab has a strong anti-tumor activity .
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1
1 Cited Publications
Cat. No.: HY-P99700
CAS No.: 2283356-07-8
Synonyms: IBI-188

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Letaplimab (IBI-188) is a human IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis .
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1
1 Cited Publications
Cat. No.: HY-P72917
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3; CD47 Antigen; CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer); Protein MER6; CD47 Molecule; Integrin Associated Protein
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7831
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD47; Antigen Identified By Monoclonal Antibody 1D8; Prev. MER6; Integrin-Associated Protein; Leukocyte Surface Antigen CD47; Rh-Related Antigen; IAP; CD47 Glycoprotein; Antigenic Surface Determinant Protein OA3; Integrin-Associated Signal Transducer; OA3
Species:  
Rhesus Macaque;Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P99175
CAS No.: 2243227-60-1

Target:  

CD47

Research Areas:  

Cancer

KWAR23 is an anti-human SIRPα antibody. KWAR23 binds human SIRPα with high affinity and disrupts its binding to CD47. KWAR23 shows antitumor activity in combination with tumor-opsonizing antibodies and can be used in cancer immunotherapy research .
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Cat. No.: HY-P990858

Target:  

CD47

Research Areas:  

Cancer

Anti-CD47 Antibody (B6.H12) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD47. Anti-CD47 Antibody (B6.H12) blocks CD47 interactions with SIRPα. Anti-CD47 Antibody (B6.H12) inhibits cell proliferation, cell migration and invasion. Anti-CD47 Antibody (B6.H12) increases macrophage phagocytosis. Anti-CD47 Antibody (B6.H12) shows potent anti-tumor effect in various tumor models, such as osteosarcoma .
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Cat. No.: HY-P991023
CAS No.: 2911590-72-0
Synonyms: 6MW3211

Target:  

CD47 PD-1/PD-L1

Research Areas:  

Cancer

Safimestomig (6MW3211) is an CD47/PD-L1-targeting bispecific antibody. Safimestomig blocks CD47-mediated 'don't eat me' signaling and selectively binds to CD47 on tumor cells. Safimestomig blocks PD-L1-mediated immune checkpoint signaling. Safimestomig can be used for the research of cancer .
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Cat. No.: HY-P990132

Target:  

CD47

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) is an anti-mouse/rat/human CD47/IAP IgG1 monoclonal antibody. Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) can effectively block CD47 signaling and enhance macrophage phagocytic function. Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) can increase the infiltration of immune cells. Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) may interfere with wound healing. Anti-Mouse/Rat/Human CD47/IAP Antibody (MIAP410) can be used for researches on cancer and inflammation conditions such as breast cancer and intestinal mucosal repair .
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Cat. No.: HY-P99172
CAS No.: 2085844-54-6

Research Areas:  

Cancer

CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar Kd value. CC-90002 can be used for the research of hematologic malignancies and solid tumors .
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Cat. No.: HY-P99903
CAS No.: 2378862-90-7
Synonyms: IBI-322

Target:  

PD-1/PD-L1 CD47

Research Areas:  

Inflammation/Immunology Cancer

Simridarlimab (IBI-322) is a bispecific antibody targeting PD-L1 and CD47. Simridarlimab attenuates CD47 activity in monovalent binding and blockes PD-L1 activity in bivalent binding. Simridarlimab selectively binds to CD47+PD-L1+ tumor cells, effectively inhibits CD47-SIRPα signal and triggered strong tumor cell phagocytosis in vitro .
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Cat. No.: HY-P990694
CAS No.: 2607644-43-7
Synonyms: TG-1801

Target:  

CD19 CD47

Research Areas:  

Inflammation/Immunology

Zeripatamig is an anti-CD19/CD47 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991085

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

HX009 is a bispecific antibody targeting PD1 and CD47, but with weakened CD47 binding. HX009 blocks the functional of PD1/CD47. HX009 can be used for the study of non-Hodgkin’s lymphoma (NHL) .
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Cat. No.: HY-P991057
CAS No.: 2376730-61-7

Target:  

CD47

Research Areas:  

Cancer

STI-6643 is a fully human IgG4 antibody that targets CD47. STI-6643 blocks CD47-SIRPα interaction, and enables macrophage-mediated phagocytosis of tumor cells. STI-6643 shows anti-tumor activity in mouse lymphoma xenograft models. STI-6643 can be used for the research of Burkitt's lymphoma, solid tumors, relapsed or refractory tumors, and lymphoma. The isotype control for STI-6643 can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P990289

Research Areas:  

Infection

Anti-Mouse CD172a Antibody (P84) is a rat-derived anti-mouse CD172a IgG1 κ type antibody inhibitor. Anti-Mouse CD172a Antibody (P84) blocks CD47-SIRPα interaction and thereby augments cell phagocytosis. Anti-Mouse CD172a Antibody (P84) can be used for the researches of infection and immunology, such as salmonella typhimurium infection .
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Cat. No.: HY-P991062
Synonyms: Gensci-059

Target:  

CD47

Research Areas:  

Cancer

Gentulizumab (Gensci-059) is a humanized IgG4 antibody that targets CD47. Gentulizumab displays strong binding to CD47 in both human and monkey, and effectively inhibits the CD47-SIRPα interaction. Gentulizumab exhibits a potent antitumor activity. The isotype control for Gentulizumab can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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Cat. No.: HY-P991755

Target:  

CD47

Anti-Rat CD47 Antibody (OX-101) reacts with CD47. Anti-Rat CD47 Antibody (OX-101) accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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