Zeripatamig
Based on 1 Customer Validation
Zeripatamig is an anti-CD19/CD47 human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
For research use only. We do not sell to patients.
- Purity: ≥99.0%
- CAS No.: 2607644-43-7
- Molecular Weight:143.846 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IgG1-lambda-kappa
Human
CD19 & CD47
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
P11609 & Q61735-1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-lambda-kappa
ELISA, FACS, Functional assay
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Flow cytometric analysis of 1X106 Raji cells with Zeripatamig (HY-P990694, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Flow cytometric analysis of 1X106 Jurkat cells with Zeripatamig (HY-P990694, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Loaded Zeripatamig on AHC2 biosensor, can bind CD47 Protein, Human (HEK293, His, HY-P7336) with an affinity constant of 1.692E-08 M as determined in BLI assay. -
Loaded Zeripatamig on AHC2 biosensor, can bind CD19 Protein, Human (HEK293, His, HY-P74330) with an affinity constant of 2.935E-09 M as determined in BLI assay.
Chemical Information
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CAS No. 2607644-43-7
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Appearance Liquid
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Molecular Weight 143.846 kDa
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Color Colorless to light yellow
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Synonyms
TG-1801
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Zeripatamig
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)