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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
CDC-like kinase 1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "CDC-like kinase 1" in MCE Product Catalog:
1
1 Cited Publications
Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM) .
Cat. No.: HY-400528
CAS No.: 332939-32-9
Target:
Research Areas:
CLK1-IN-4 (Compound 81) is an inhibitor for CDC like kinase 1 (CLK-1) with IC50 of 2.5 μM .
Cat. No.: HY-179177
CAS No.: 1081122-55-5
Target:
Research Areas:
AO-365/43472821 is a selective, brain-penetrant Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitor (IC50 = 0.29 μM) and shows a significant inhibitory effect on (CDC-like kinase 1) CLK1 (IC50 = 0.08 μM). AO-365/43472821 could protect the human neuroblastoma cell line SH-SY5Y from Okadaic acid (HY-N6785) (OA)-induced injury. AO-365/43472821 decreased tau (pSer396)/tau and Aβ1-42 protein expression. AO-365/43472821 can be used for the study of Alzheimer's disease .
Cat. No.: HY-P705761
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CLK1; Protein Tyrosine kinase STY; CDC like kinase 1; Dual-Specificity kinase; Dual Specificity Protein kinase CLK1; CDC28/CDC2-like kinase; CDC-like kinase 1; CLK/STY; CLK; STY
Species:
Human
Source:
sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
