1481617-15-5

Ipivivint Chemical Structure
1481617-15-5

Chemical Structure

Ipivivint

  • CAS No.: 1481617-15-5
  • Formula:C26H21FN8
  • Molecular Weight:464.50

IUPAC Name: 1-(5-(3-(7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yl)-N,N-dimethylmethanamine

InChIKey: YBBUGSYNPXTSGW-UHFFFAOYSA-N

SMILES: CN(C)CC1=CC(C2=CN=C(NN=C3C(N4)=NC5=C4C(C6=CC(F)=CC=C6)=CN=C5)C3=C2)=CN=C1

Biological Activity: Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM)[1][2].

Cat. No. Product Name Purity Description Pricing
HY-137443
Ipivivint 99.95% Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM).
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