1 Result for "

CDK4/6-IN-26

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CDK4/6-IN-26" in MCE Product Catalog:

Cat. No.: HY-179151
Research Areas:  

Cancer

CDK4/6-IN-26 is a carbamate derivative that targets CDK4/CDK6. CDK4/6-IN-26 reduces CDK4/CDK6 levels, resulting in cell cycle arrest in the G0/G1 phase and in the S phase. CDK4/6-IN-26 exhibits high potency against SW480 cells (IC50 = 6.3 μM). CDK4/6-IN-26 affects ROS levels by increasing the expression of SOD2/MnSOD. CDK4/6-IN-26 establishes several interactions with the amino acids of the CDK6 active site. CDK4/6-IN-26 can be used for the research of colorectal cancer .
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